Now showing items 1-8 of 8

    • Anthocyanin composition in aged Chilean Cabernet Sauvignon red wines 

      Aguirre, María J.; Isaacs, Mauricio; Matsuhiro, Betty; Mendoza, Leonora; Santos, Leonardo S.; Torres, Simonet (2011)
      Anthocyanins in aged Cabernet Sauvignon red wines were studied by HPLC-MS. The major anthocyanin in 6, 7, and 8 year old red wine extracts was the dimer vitisin A produced by condensation of malvidin-3-O-glucoside mediated ...
    • Correlating experimental electrochemistry and theoretical calculations in 2 '-hydroxy chalcones: the role of the intramolecular hydrogen bond 

      Martínez Cifuentes, Maximiliano; Salazar, Ricardo; Escobar, Carlos A.; Weiss López, Boris; Santos, Leonardo S.; Araya Maturana, Ramiro (Royal Soc Chemistry, 2015)
      In this work we present a study on the molecular structure and electrochemical behavior of a series of methoxylated 2'-hydroxychalcones, whose antitumor activity has been previously described. Cyclic voltammetry was used ...
    • Heterocyclic curcumin derivatives of pharmacological interest: Recent progress 

      Martínez Cifuentes, Maximiliano; Weiss López, Boris; Santos, Leonardo S.; Araya Maturana, Ramiro (Bentham Science Publishers B.V., 2015)
      © 2015, Bentham Science Publishers. Curcumin, a natural yellow polyphenol, is isolated from the herb Curcuma longa L. (turmeric), a member of the ginger family. It has been extensively studied due to their multiple ...
    • Intermolecular stabilization in new 2-iminopyridine derivatives complexes of Pd(II) and their reactivity towards alkenes 

      Escobar, Manuel A.; Moreno da Costa, David; Trofymchuk, Oleksandra S.; Daniliuc, Constantin G.; Gracia, Francisco; Nachtigall, Fabiane M.; Santos, Leonardo S.; Rojas, Rene S.; Cabrera, Alan R. (Elsevier, 2018)
      Two new iminopyriridine ligands (1-2) and two new neutral Pd(II) complexes (4-5) were designed, synthesized and characterized by spectroscopic and spectrometric techniques. Molecular structures of compounds 1, 3 and 5 were ...
    • Intramolecular hydrogen bond in biologically active o-carbonyl hydroquinones 

      Martínez Cifuentes, Maximiliano; Weiss López, Boris; Santos, Leonardo S.; Araya Maturana, Ramiro (MDPI, 2014)
      Intramolecular hydrogen bonds (IHBs) play a central role in the molecular structure, chemical reactivity and interactions of biologically active molecules. Here, we study the IHBs of seven related o-carbonyl hydroquinones ...
    • Nanoinformatics: an emerging area of information technology at the intersection of bioinformatics, computational chemistry and nanobiotechnology 

      González Nilo, Fernando; Pérez Acle, Tomás; Guínez Molinos, Sergio; Geraldo, Daniela A.; Sandoval, Claudia; Yévenes, Alejandro; Santos, Leonardo S.; Laurie, V. Felipe; Mendoza, Hegaly; Cachau, Raúl E. (SOC BIOLGIA CHILE, 2011)
      After the progress made during the genomics era, bioinformatics was tasked with supporting the fl ow of information generated by nanobiotechnology efforts. This challenge requires adapting classical bioinformatic and ...
    • Rational development of a novel hydrogel as a pH-sensitive controlled release system for nifedipine 

      Avila-Salas, Fabián; Rodriguez Nuñez, Yeray A.; Marican, Adolfo; Castro, Ricardo I.; Villaseñor, Jorge; Santos, Leonardo S.; Wehinger, Sergio; Durán-Lara, Esteban F. (MDPI AG, 2018)
      © 2018 by the authors. This work depicts the rational development (in-silico design, synthesis, characterization and in-vitro evaluation) of polyvinyl alcohol hydrogels (PVAH) cross-linked with maleic acid (MA) and linked ...
    • Reactivity of 3-sulfanyl-1-hexanol and catechol-containing phenolics in vitro 

      Laurie, V. Felipe; Zúñiga, María C.; Carrasco Sánchez, Verónica; Santos, Leonardo S.; Cañete, Álvaro; Olea Azar, Claudio; Ugliano, Maurizio; Agosin Trumper, Eduardo (Elsevier, 2012)
      Volatile species with thiol functions are important contributors to the flavour of a wide variety of wine types. However, in spite of their importance, their fate during winemaking has not been fully elucidated. In this ...