Browsing by Author "fa9d62b3-ace1-4389-9d3b-5a693f0ad40c"
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A functional IL1RL1 variant regulates corticosteroid-induced sST2 expression in ulcerative colitis Díaz Jiménez, David; Núñez, Lucía; Fuente, Marjorie de la; Dubois Camacho, Karen; Sepulveda, Hugo; Montecino, Martin; Torres Riquelme, Alejandro; García González, Paulina; Chnaiderman Figueroa, Jonás; Vossenkamper, Anna; MacDonald, Thomas T.; Simian, Daniela; González Burgos, María Julieta; Cidlowski, John A.; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (Nature Publishing Group, 2017)The ST2/IL33 signalling pathway has been associated with ulcerative colitis (UC). ST2, encoded by the IL1RL1 gene, is expressed as both a membrane-anchored receptor (ST2L) activated by IL33 and as a soluble receptor (sST2) ...
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López Aguilar, Rodrigo; Bustos, Fernando J.; Sáez, Mauricio; Rojas, Adriana; Allende Connelly, Miguel; van Wijnen, Andre J.; van Zundert, Brigitte; Montecino, Martín (Elsevier, 2016)During hippocampal neuron differentiation, the expression of critical inducers of non-neuronal cell lineages must be efficiently silenced. Runx2 transcription factor is the master regulator of mesenchymal cells responsible ...