Browsing by Author "ff916f5b-71ce-4b1e-9875-4568892ed53c"

Now showing items 1-7 of 7

    • Caveolin-1 expression increases upon maturation in dendritic cells and promotes their migration to lymph ... 
      Oyarce, César; Cruz Gómez, Sebastián; Gálvez Cancino, Felipe Ignacio; Vargas, Pablo; Moreau, Hélène D.; Díaz Valdivia, Natalia; Díaz, Jorge; Salazar Onfray, Flavio; Pacheco, Rodrigo; Lennon Duménil, Ana María; Quest, Andrew F. G.; Lladser, Álvaro (Frontiers Media, 2017)
      Dendritic cell (DC) trafficking from peripheral tissues to lymph nodes (LNs) is a key step required to initiate T cell responses against pathogens as well as tumors. In this context, cellular membrane protrusions and the ...
    • Dendritic cells are crucial for cardiovascular remodeling and modulate neutrophil gelatinase-associated ... 
      Araos, Patricio; Prado, Carolina; Lozano, Mauricio; Figueroa, Stefanny; Espinoza, Alexandra; Berger, Thorsten; Mak, Tak W.; Jaisser, Frédéric; Pacheco, Rodrigo; Michea Acevedo, Luis; Amador, Cristián A. (Lippincott Williams and Wilkins, 2019)
      Background:Adaptive immunity is crucial in cardiovascular and renal inflammation/fibrosis upon hyperactivation of mineralocorticoid receptor. We have previously demonstrated that dendritic cells can respond to mineralocorticoid ...
    • Dopamine receptor D3 expression is altered in CD4+ T-cells from Parkinson's disease patients and its ... 
      Elgueta, Daniela; Contreras, Francisco; Prado, Carolina; Montoya, Andro; Ugalde, Valentina; Chovar, Ornella; Villagra, Roque; Henríquez, Claudio; Abellanas, Miguel A.; Aymerich, María S.; Franco, Rarael; Pacheco, Rodrigo (Frontiers Media S.A., 2019)
      Copyright © 2019 Elgueta, Contreras, Prado, Montoya, Ugalde, Chovar, Villagra, Henríquez, Abellanas, Aymerich, Franco and Pacheco. This is an open-access article distributed under the terms of the Creative Commons Attribution ...
    • Dopamine Receptor D3 Signaling on CD4(+) T Cells Favors Th1-and Th17-Mediated Immunity 
      Contreras, Francisco; Prado, Carolina; González, Hugo; Franz, Dafne; Osorio Barrios, Francisco; Osorio Olivares, Fabiola; Ugalde, Valentina; López, Ernesto; Elgueta, Daniela; Figueroa, Alicia; Lladser, Álvaro; Pacheco, Rodrigo (Amer Assoc Immunologists, 2016)
      Dopamine receptor D3 (DRD3) expressed on CD4(+) T cells is required to promote neuroinflammation in a murine model of Parkinson's disease. However, how DRD3 signaling affects T cell-mediated immunity remains unknown. In ...
    • Galectin-8 as an immunosuppressor in experimental autoimmune encephalomyelitis and a target of human early ... 
      Pardo, Evelyn; Carcamo, Claudia; Uribe San Martin, Reinaldo; Ciampi, Ethel; Segovia Miranda, Fabián; Curkovic Peña, Cristobal; Montecino, Fabián; Holmes, Christopher; Tichauer, Juan E.; Acuña, Eric; Osorio Barrios, Francisco; Castro, Marjorie; Cortes, Priscilla; Oyanadel, Claudia; Valenzuela, David M.; Pacheco, Rodrigo; Naves Pichuante, Rodrigo Antonio; Soza, Andrea; González, Alfonso (Public Library Science, 2017)
      Galectin-8 (Gal-8) is a member of a glycan-binding protein family that regulates the immune system, among other functions, and is a target of antibodies in autoimmune disorders. However, its role in multiple sclerosis (MS), ...
    • IRE1α activation in bone marrow-derived dendritic cells modulates innate recognition of melanoma cells and ... 
      Medel, Bernardita; Costoya, Cristobal; Fernandez, Dominique; Pereda, Cristian; Lladser, Alvaro; Sauma, Daniela; Pacheco, Rodrigo; Iwawaki, Takao; Salazar Onfray, Flavio; Osorio, Fabiola (Frontiers Media S.A., 2019)
      The IRE1α/XBP1s signaling pathway is an arm of the unfolded protein response (UPR) that safeguards the fidelity of the cellular proteome during endoplasmic reticulum (ER) stress, and that has also emerged as a key regulator ...
    • The histone demethylase inhibitor GSK-J4 limits inflammation through the induction of a tolerogenic phenotype ... 
      Doñas, Cristian; Carrasco, Macarena; Fritz, Macarena; Ríos del Prado, Carolina Alejandra; Tejón, Gabriela; Osorio Barrios, Francisco; Manríquez, Valeria; Reyes, Paz; Pacheco, Rodrigo; Bono Merino, María Rosa; Loyola, Alejandra; Rosemblatt Silber, Mario César (Academic Press, 2016)
      © 2016 The Authors As it has been established that demethylation of lysine 27 of histone H3 by the lysine-specific demethylase JMJD3 increases immune responses and thus elicits inflammation, we hypothesize that inhibition ...