Now showing items 21-40 of 40

    • Murad, Mohammad Hassan; Montori, Victor M.; Ioannidis, John P A; Jaeschke, Roman; Devereaux, P. J.; Prasad, Kameshwar; Neumann, Ignacio; Carrasco Labra, Alonso; Agoritsas, Thomas; Hatala, Rose; Meade, Maureen O.; Wyer, Peter; Cook, Deborah J.; Guyatt, Gordon H. (American Medical Association, 2014)
      Clinical decisions should be based on the totality of the best evidence and not the results of individual studies. When clinicians apply the results of a systematic review or meta-analysis to patient care, they should start ...
    • Zhang, Yuqing; Montoya, Luis; Ebrahim, Shanil; Busse, Jason W.; Couban, Rachel; McCabe, Randi E.; Bieling, Peter; Carrasco Labra, Alonso; Guyatt, Gordon H. (QUINTESSENCE PUBLISHING, 2015)
      Aims: To conduct a systematic review and meta-analysis to evaluate the effectiveness of hypnosis/relaxation therapy compared to no/minimal treatment in patients with temporomandibular disorders (TMD). Methods: Studies ...
    • Brignardello Petersen, Romina; Carrasco Labra, Alonso; Araya, Ignacio; Yanine, Nicolas; Beyene, Joseph; Shah, Prakesh (2012)
      Purpose: To assess the efficacy and safety of low-level laser energy irradiation (LLEI) for decreasing pain, swelling, and trismus after surgical removal of impacted mandibular third molars (IMTMs). Materials and Methods: ...
    • Johnston, Bradley C.; Ebrahim, Shanil; Carrasco Labra, Alonso; Furukawa, Toshi A.; Patrick, Donald L.; Crawford, Mark W.; Hemmelgarn, Brenda R.; Schunemann, Holger J.; Guyatt, Gordon H.; Nesrallah, Gihad (BMJ Publishing Group, 2015)
      Introduction Patient-reported outcomes (PROs) are often the outcomes of greatest importance to patients. The minimally important difference (MID) provides a measure of the smallest change in the PRO that patients perceive ...
    • Ebrahim, Shanil; Vercammen, Kelsey; Sivanand, Arunima; Guyatt, Gordon H.; Carrasco Labra, Alonso; Fernandes, Ricardo M.; Crawford, Mark W.; Nesrallah, Gihad; Johnston, Bradley C. (American Academy of Pediatrics, 2017)
      Copyright © 2017 by the American Academyof Pediatrics. All rights reserved. CONTEXT: No study has characterized and appraised all anchor-based minimally important differences (MIDs) associated with patient-reported outcome ...
    • Brignardello Petersen, Romina; Carrasco Labra, Alonso; Glick, Michael; Guyatt, Gordon H.; Azarpazhooh, Amir (AMER DENTAL ASSOC, 2015)
      Background and Overview. Dental practitioners spend most of their time administering treatments. To ensure that their clinical decisions are informed by the best available evidence, dental practitioners need to be skilled ...
    • Brignardello Petersen, Romina; Carrasco Labra, Alonso; Glick, Michael; Guyatt, Gordon H.; Azarpazhooh, Amir (Amer Dental Assoc, 2015)
      Background and Overview. Questions regarding harm are common in dental practice. Observational, nonrandomized studies (that is, cohort studies and casecontrol studies) are the designs used by investigators to answer most ...
    • Abrahamyan, Lusine; Pechlivanoglou, Petros; Krahn, Murray; Carrasco Labra, Alonso; Brignardello Petersen, Romina; Glick, Michael; Guyatt, Gordon H.; Azarpazhooh, Amir (American Dental Association, 2015)
      Background and Overview. In everyday practice, dentists face clinical decisions for which they need to consider both treatment consequences (that is, benefits and harms) and costs. Economic analysis is a study design in ...
    • Brignardello Petersen, Romina; Carrasco Labra, Alonso; Glick, Michael; Guyatt, Gordon H.; Azarpazhooh, Amir (Amer Dental Assoc, 2015)
      Background and Overview. Questions regarding diagnosis are common in dental practice. Studies in which investigators apply a diagnostic test and a reference standard to all patients and compare their results represent the ...
    • Sale, Joanna E. M; Amin, Maryam; Carrasco Labra, Alonso; Brignardello Petersen, Romina; Glick, Michael; Guyatt, Gordon H.; Azarpazhooh, Amir (Amer Dental Assoc, 2015)
      Background and Overview. Because of qualitative researchers' abilities to explore social problems and to understand the perspective of patients, qualitative research studies are useful to provide insight about patients' ...
    • Schandelmaier, Stefan; Elm, Erik von; You, John J.; Bluemle, Anette; Tomonaga, Yuki; Lamontagne, Francois; Saccilotto, Ramón; Amstutz, Alain; Bengough, Theresa; Meerpohl, Joerg J.; Stegert, Mihaela; Olu, Kelechi K.; Tikkinen, Kari A. O.; Neumann, Ignacio; Carrasco Labra, Alonso; Faulhaber, Markus; Mulla, Sohail M.; Mertz, Dominik; Akl, Elie A.; Sun, Xin; Bassler, Dirk; Busse, Jason W.; Ferreira González, Ignacio; Nordmann, Alain; Gloy, Viktoria; Raatz, Heike; Moja, Lorenzo; Rosenthal, Rachel; Ebrahim, Shanil; Vandvik, Per O.; Johnston, Bradley C.; Walter, Martin A.; Burnand, Bernard; Schwenkglenks, Matthias; Hemkens, Lars G.; Cook, Deborah J.; Meade, Maureen O.; Bucher, Heiner C.; Kasenda, Benjamin; Briel, Matthias (Lippicott Williams & Wilkins, 2016)
      Objectives: Randomized clinical trials that enroll patients in critical or emergency care (acute care) setting are challenging because of narrow time windows for recruitment and the inability of many patients to provide ...
    • Kasenda, Benjamin; Von Elm, Erik; You, John; Blümle, Anette; Tomonaga, Yuki; Saccilotto, Ramón; Amstutz, Alain; Bengough, Theresa; Meerpohl, Joerg J.; Stegert, Mihaela; Tikkinen, Kari A. O.; Neumann, Ignacio; Carrasco Labra, Alonso; Faulhaber, Markus; Mulla, Sohail M.; Mertz, Dominik; Akl, Elie A.; Bassler, Dirk; Busse, Jason W.; Ferreira González, Ignacio; Lamontagne, Francois; Nordmann, Alain; Gloy, Viktoria; Raatz, Heike; Moja, Lorenzo; Rosenthal, Rachel; Ebrahim, Shanil; Schandelmaier, Stefan; Xin, Sun; Vandvik, Per O.; Johnston, Bradley C.; Walter, Martin A.; Burnand, Bernard; Schwenkglenks, Matthias; Hemkens, Lars G.; Bucher, Heiner C.; Guyatt, Gordon H.; Briel, Matthias (American Medical Association., 2014)
      IMPORTANCE The discontinuation of randomized clinical trials (RCTs) raises ethical concerns and often wastes scarce research resources. The epidemiology of discontinued RCTs, however, remains unclear. OBJECTIVES To ...
    • Carrasco Labra, Alonso; Brignardello Petersen, Romina; Yanine, Nicolás; Araya, Ignacio; Rada, Gabriel; Graham Chadwick, R. (John Wiley and Sons Ltd, 2013)
      This is the protocol for a review and there is no abstract. The objectives are as follows: To assess the effects of tooth whitening products developed to be professionally-applied with chemical, bleaching action (in-office). ...
    • Akl, Elie A; Shawwa, Khaled; Kahale, Lara A.; Agoritsas, Thomas; Brignardello Petersen, Romina; Busse, Jason W.; Carrasco Labra, Alonso; Ebrahim, Shanil; Johnston, Bradley C.; Neumann, Ignacio; Solà, Iván; Sun, Xin; Vandvik, Per; Zhang, Yuqing; Alonso Coello, Pablo; Guyatt, Gordon H. (BMJ Publishing Group, 2015)
      Objectives We conducted a systematic survey of the methodological literature to identify recommended approaches for how and what randomised clinical trial (RCT) authors should report on missing participant data and, on the ...
    • Akl, Elie A.; Carrasco Labra, Alonso; Brignardello Petersen, Romina; Neumann, Ignacio; Johnston, Bradley C.; Sun, Xin; Briel, Matthias; Busse, Jason W.; Ebrahim, Shanil; Granados, Carlos E.; Iorio, Alfonso; Irfan, Affan; Martínez García, Laura; Mustafa, Reem A.; Ramírez Morera, Anggie; Selva, Anna; Solà, Iván; Sanabria, Andrea Juliana; Tikkinen, Kari A. O.; Vandvik, Per O.; Vernooij, Robin W. M.; Zazueta, Oscar E.; Zhou, Qi; Guyatt, Gordon H.; Alonso Coello, Pablo (BMJ, 2015)
      Objectives: To describe how systematic reviewers are reporting missing data for dichotomous outcomes, handling them in the analysis and assessing the risk of associated bias. Methods: We searched MEDLINE and the Cochrane ...
    • Carrasco Labra, Alonso; Brignardello Petersen, Romina; Yanine, Nicolás; Araya, Ignacio; Guyatt, Gordon (2012)
      Purpose: To determine the impact of secondary versus primary closure techniques on the frequency and severity of pain, facial swelling, trismus, infectious complications, and postoperative bleeding after impacted mandibular ...
    • Alonso Coello, Pablo; Carrasco Labra, Alonso; Brignardello Petersen, Romina; Neumann, Ignacio; Akl, Elie; Vernooij, Robin; Johnston, Brad; Sun, Xin; Briel, Matthias; Busse, Jason; Ebrahim, Shanil; Granados, Carlos; Iorio, Alfonso; Irfan, Affan; Martínez García, Laura; Mustafa, Reem; Ramírez Morers, Anggie; Selva, Anna; Solà, Iván; Sanabria, Andrea; Tikkinen, Kari; Vandvik, Per; Zazueta, Oscar; Zhang, Yuqing; Zhou, Qi; Schünemann, Holger; Guyatt, Gordon H. (Elsevier, 2016)
      Objectives: Expressing treatment effects in relative terms yields larger numbers than expressions in absolute terms, affecting the judgment of the clinicians and patients regarding the treatment options. It is uncertain ...
    • Salazar Núñez, Josefina Paz (Universidad de Chile, 2017)
      RESUMEN Introducción: El número de pacientes que se encuentran en tratamiento con antiagregantes plaquetarios (TAP) ha ido en aumento las últimas décadas. Los beneficios de la interrupción del TAP previo a procedimientos ...
    • Ebrahim, Shanil; Montoya, Luis; Busse, Jason; Carrasco Labra, Alonso; Guyatt, Gordon H. (American Dental Association, 2012)
      Purpose The authors conducted a systematic review of all published randomized controlled trials in which investigators compared the effectiveness of splint therapy with that of minimal or no treatment in patients with ...
    • Neumann, Ignacio; Brignardello Petersen, Romina; Wiercioch, Wojtek; Carrasco Labra, Alonso; Cuello, Carlos; Akl, Elie A; Mustafa, Reem; Al-Hazzani, Waleed; Etxeandia-Ikobaltzeta, Itziar; Rojas, María; Falavigna, Maicon; Santesso, Nancy; Brozek, Jan; Iorio, Alf; Alonso-Coello, Pablo; Schünemann, Holger (BioMed Central Ltd., 2016)
      Background: Judgments underlying guideline recommendations are seldom recorded and presented in a systematic fashion. The GRADE Evidence-to-Decision Framework (EtD) offers a transparent way to record and report guideline ...