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Now showing items 33326-33345 of 92058

    • Epigenetic and birth 
      Ortiz Contreras, Jovita; Paredes, Daniela; Neira Contreras, Rodrigo; Gálvez Ortega, Pablo Francisco (MedCrave, 2017)
      Epigenetics refers to the study of how genes express their phenotypic effect, all of which can be modified by the environment. Recently, pregnancy, labour and birth have been proposed as critical periods of exposure to ...
    • Epigenetic and phenotypic changes result from a continuous pre and post natal dietary exposure to phytoestrogens ... 
      Guerrero-Bosagna, Calos M.; Sabat Kirkwood, Alejandro Pablo; Valdovinos, Fernanda S.; Valladares Boasi, Luis; Clark, Susan J. (BioMed Central, 2008-09-15)
      Background: Developmental effects of exposure to endocrine disruptors can influence adult characters in mammals, but could also have evolutionary consequences. The aim of this study was to simulate an environmental ...
    • Epigenetic and Transcriptional Alterations in Human Adipose Tissue of Polycystic Ovary Syndrome 
      Kokosar, Milana; Benrick, Anna; Perfilyev, Alexander; Fornes, Romina; Nilsson, Emma; Maliqueo Yevilao, Manuel; Behre, Carl Johan; Sazonova, Antonina; Ohlsson, Claes; Ling, Charlotte; Stener-Victorin, Elisabet (Nature Publishing Group, 2016)
      Genetic and epigenetic factors may predispose women to polycystic ovary syndrome (PCOS), a common heritable disorder of unclear etiology. Here we investigated differences in genome-wide gene expression and DNA methylation ...
    • Epigenetic Control of the Bone-master Runx2 Gene during Osteoblast-lineage Commitment by the Histone ... 
      Rojas, Adriana; Aguilar, Rodrigo; Henríquez, Berta; Lian, Jane B.; Stein, Janet L.; Stein, Gary S.; Wijnen, Andre J. van; Zundert, Brigitte van; Allende Connelly, Miguel; Montecino, Martín (The American Society for Biochemistry and Molecular Biology, 2015)
      Transcription factor Runx2 controls bone development and osteoblast differentiation by regulating expression of a significant number of bone-related target genes. Here, we report that transcriptional activation and repression ...
    • Epigenetic footprint enables molecular risk stratification of hepatoblastoma with clinical implications 
      Carrillo Reixach, Juan; Torrens, Laura; Simon Coma, Marina; Royo, Laura; Domingo Sàbat, Montserrat; Abril Fornaguera, Jordi; Akers, Nicholas; Sala, Margarita; Ragull, Sonia; Arnal, Magdalena; Villalmanzo, Núria; Cairo, Stefano; Villanueva, Alberto; Kappler, Roland; Garrido, Marta; Guerra, Laura; Sábado, Constantino; Guillén, Gabriela; Mallo, Mar; Piñeyro, David; Vázquez Vitali, María; Kuchuk, Olga; Mateos, María Elena; Ramírez, Gema; López Santamaría, Manuel; Mozo, Yasmina; Soriano, Aroa; Grotzer, Michael; Branchereau, Sophie; García de Andoin, Nagore; López Ibor, Blanca; López Almaraz, Ricardo; Salinas, José Antonio; Torres, Bárbara; Hernández, Francisco; Uriz, José Javier; Fabre, Monique; Blanco, Julià; Paris Domínguez, Claudia; Bajčiová, Viera; Laureys, Geneviève; Masnou, Helena; Clos, Ariadna; Belendez, Cristina; Guettier, Catherine; Sumoy, Lauro; Planas, Ramón; Jordà, Mireia; Nonell, Lara; Czauderna, Piotr; Morland, Bruce; Sia, Daniela; Losic, Borjan; Buendia, Marie Annick; Sarrias, María Rosa; Llovet, Josep M.; Armengol, Carolina (Elsevier, 2020)
      Background & Aims: Hepatoblastoma (HB) is a rare disease. Nevertheless, it is the predominant pediatric liver cancer, with limited therapeutic options for patients with aggressive tumors. Herein, we aimed to uncover the ...
    • Epigenetic mechanisms involved in cisplatin-induced nephrotoxicity: An update 
      Loren, Pía; Saavedra, Nicolás; Saavedra, Kathleen; Zambrano Coloma, Tomas Andrés; Moriel, Patricia; Salazar, Luis A. (MDPI, 2021)
      Cisplatin is an antineoplastic drug used for the treatment of many solid tumors. Among its various side effects, nephrotoxicity is the most detrimental. In recent years, epigenetic regulation has emerged as a modulatory ...
    • Epigenetic Programming of Cardiovascular Disease by Perinatal Hypoxia and Fetal Growth Restriction 
      Casanello, Paola; Herrera Videla, Emilio; Krause, Bernardo J. (INTECH, 2017)
      Most of the worldwide deaths in patients with non-communicable diseases are due to cardiovascular and metabolic diseases, which are determined by a mix of environmental, genetic and epigenetic factors, and by their ...
    • Epigenetic Reader BRD4 (Bromodomain-Containing Protein 4) Governs Nucleus-Encoded Mitochondrial Transcriptome ... 
      Kim, Soo Young; Zhang, Xin; Schiattarella, Gabriele G.; Altamirano, Francisco; Ramos, Thais; French, Kristin M.; Jiang, Nan; Szweda, Pamela A.; Evers, Bret M.; May, Herman; Luo, Xiang; Li, Hongliang; Szweda, Luke; Maracajá Coutinho, Vinicius; Lavandero González, Sergio; Gillette, Thomas G.; Hill, Joseph A. (Lippincott Williams & Wilkins, 2020)
      BACKGROUND: BET (bromodomain and extraterminal) epigenetic reader proteins, in particular BRD4 (bromodomain-containing protein 4), have emerged as potential therapeutic targets in a number of pathological conditions, ...
    • Epigenetic regulation of folate receptor-alpha (FOLR1) in human placenta of preterm newborns 
      Piñuñuri Flores, Raúl; Castaño Moreno, Erika; Llanos Silva, Miguel; Ronco Macchiavello, Ana María (Elsevier, 2020)
      Introduction: Folates are essential nutrients for fetal development and pregnancy outcomes; they are transported to the fetus during gestation through specific folate transporters located in the placenta. In preterm newborns, ...
    • Epigenetic regulation of TLR2-mediated periapical inflammation 
      Fernandez, A; Veloso, P; Astorga, J; Rodriguez, C; Torres, VA; Valdes, M; Garrido, M; Gebicke-Haerter, PJ; Hernandez, M (Blackwell Publishing Ltd, 2020)
    • Epigenetic signatures at the RUNX2-P1 and Sp7 gene promoters control osteogenic lineage commitment of ... 
      Sepulveda, Hugo; Aguilar, Rodrigo; Prieto, Catalina P.; Bustos, Francisco; Aedo Monsalve, Sócrates; Lattus Olmos, José; Van Zundert, Brigitte; Palma, Verónica; Montecino, Martín (Wiley, 2017)
      Wharton's Jelly mesenchymal stem cells (WJ-MSCs) are an attractive potential source of multipotent stem cells for bone tissue replacement therapies. However, the molecular mechanisms involved in their osteogenic conversion ...
    • Epigenetics in type 1 diabetes: TNFa gene promoter methylation status in Chilean patients with type 1 ... 
      Arroyo Jousse, Viviana; García Díaz, Diego; Codner Dujovne, Ethel; Pérez Bravo, Francisco (Cambridge University Press, 2016)
      © The Authors 2016. TNF-α is a pro-inflammatory cytokine that is involved in type 1 diabetes (T1D) pathogenesis. The TNFa gene is subject of epigenetic regulation in which folate and homocysteine are important molecules ...
    • Epigenética del síndrome de ovario poliquístico 
      Concha C., Francisca; Sir Petermann, Lidia; Recabarren, Sergio E.; Pérez Bravo, Fernando (Sociedad Médica de Santiago, 2017)
      Polycystic ovarian syndrome (PCOS) is an endocrine and metabolic dysfunction, highly prevalent in women in their reproductive years. Hyperandrogenism, oligo-ovulation, polycystic ovarian morphology are the main features ...
    • Epigenome-wide analysis of methylation changes in the sequence of gallstone disease, dysplasia, and gallbladder ... 
      Brägelmann, Johannes; Barahona Ponce, Carol Mariom; Marcelain Cubillos, Katherine Jenny; Roessler, Stephanie; Goeppert, Benjamín; Gallegos, Iván; Colombo, Alicia; Sanhueza, Verónica; Morales, Erik; Rivera, María Teresa; Toro, Gonzalo de; Ortega, Alejandro; Müller, Bettina; Gabler, Fernando; Scherer, Dominique; Waldenberger, Melanie; Reischl, Eva; Boekstegers, Félix; Garate Calderón, Valentina; Umu, Sinan U.; Rounge, Trine B.; Popanda, Odilia; Bermejo, Justo Lorenzo (Wiley, 2021)
      BACKGROUND AND AIMS: Gallbladder cancer (GBC) is a highly aggressive malignancy of the biliary tract. Most cases of GBC are diagnosed in low-income and middle-income countries, and research into this disease has long ...
    • Epigramas mapuches. Canto clarinete Si b Violín Cello y Piano I. Iniciación II. Pienso en mis antepasados ... 
      Cáceres Romero, Eduardo (1992)
    • Epileptic seizures after zolpidem withdrawal Crisis epilépticas post suspensión de Zolpidem 
      Castillo, JL (Sociedad Medica de Santiago, 2020)
    • Epipodium Morphology of Prisogaster niger (Mollusca: Vetigastropoda): Revealing Potential Autapomorphies ... 
      Collado, Gonzalo A.; Méndez, Marco A.; Brown, Donald I. (Universidad de la Frontera, 2012)
      In this work the epipodium morphology of the marine snail Prisogaster niger is described. In this gastropods the epipodium includes a complex of structures among which the neck lobes, epipodial ridge, epipodial tentacles ...
    • Episodes of meeting as relevant episodes for the study of change in psychotherapy 
      Duarte Soto, Alejandra Javiera (Universidad de Chile, 2017)
      The study of the change process in psychotherapy has advanced considerably during the last 30 years, focusing its efforts on the study of relevant intra-session episodes in order to contribute to a better understanding ...
    • Episodic accretion constrained by a rich cluster of outflows 
      Nony, T.; Motte, F.; Louvet, F.; Plunkett, A.; Gusdorf, A.; Fechtenbaum, S.; Pouteau, Y.; Lefloch, B.; Bontemps, S.; Molet, J.; Robitaille, J-F (EDP Sciences, 2020)
      Context. The accretion history of protostars remains widely mysterious, even though it represents one of the best ways to understand the protostellar collapse that leads to the formation of stars.Aims. Molecular outflows, ...
    • Episodic construction of the early Andean Cordillera unravelled by zircon petrochronology 
      Jara, José Joaquín; Barra Pantoja, Luis Fernando; Reich Morales, Martín Herbert; Leisen, Mathieu; Romero, Rurik; Morata Céspedes, Diego Antonio (Nature Research, 2021)
      The subduction of oceanic plates beneath continental lithosphere is responsible for continental growth and recycling of oceanic crust, promoting the formation of Cordilleran arcs. However, the processes that control the ...