Now showing items 33346-33365 of 92115

    • Collao González, Carolina; Carrasco Labra, Alonso; Sung-Hsieh, Hsiao-Hsin; Cortés Araya, Juan Eliecer (Sociedad Española de Medicina Oral, 2014-03)
      Objectives: To describe the epidemiology of facial trauma injuries in a group of Chilean children aged 15 years or less. Study Design: Retrospective study of case series. Between 2006 and 2009, clinical records of 293,090 ...
    • Lavados Germain, Pablo Manuel; Tenhamm, E. (1998)
      Objective: To describe the importance of tension-type headache (TTH) in Santiago, Chile, by analyzing its prevalence, clinical features, and impact by age, gender, and socioeconomic status, using widely accepted international ...
    • Harth, Erika; Matsuda, Luis; Hernández, Cristina; Rioseco, Maria L.; Romero Ormazábal, Jaime; González Escalona, Narjol; Martínez Urtaza, Jaime; Espejo Torres, Romilio (2009)
      Disease outbreaks caused by Vibrio parahaemolyticus in Puerto Montt, Chile, began in 2004 and reached a peak in 2005 at 3,600 clinical cases. Until 2006, every analyzed case was caused by the serovar O3:K6 pandemic strain. ...
    • Piano, S.; Singh, V.; Caraceni, P.; Roblero Cum, Juan (Elsevier, 2018)
    • Smith Schuster, Patricio C.; Santibañez, Juan F.; Morales, Juan P.; Martínez, Jorge (Blackwell Munksgaard Ltd, 2004-04-08)
      Regulation of the extracellular matrix turnover is a crucial process in wound healing and the progress of periodontal disease. It has been proposed that urokinase-type plasminogen activator (uPA), under the control of ...
    • Quevedo Pinto, Matías Ignacio (Universidad de Chile, 2007)
      La epididimitis contagiosa del carnero es una enfermedad bacteriana del ovino producida por Brucella ovis (B. ovis), que afecta mayormente el aparato genital de hembras y machos, siendo estos últimos los principales ...
    • Retamal Merino, Patricio (Universidad de Chile, Facultad de Ciencias Veterinarias y Pecuarias, 2002-12)
    • Cortés-Contreras, Maximiliano; Pizarro Araya, Jaime; Alfaro, Fermín M.; Cepeda-Pizarro, Jorge (2013)
      The coastal mountain range of Los Choros (Coquimbo Region) is a natural system with geomorphological characteristics (e.g., dunes, ravines and extensive plains at sea level) which allow for a flora and fauna adapted to ...
    • Pizarro Araya, Jaime; Alfaro, Fermín M.; Cortés-Contreras, Maximiliano; Rivera, Cristian; Vargas-Talciani, Paola; Ojanguren-Affilastro, Andrés A. (Gazi Entomological Research Society, 2014)
      The Pingüino de Humboldt National Reserve in Chile is an area of biodiversity conservation in arid island ecosystems. The reserve is located both in the Atacama and Coquimbo regions and is composed of the Choros (29° 15' ...
    • Ventura-Junca, Raúl; Herrera, Luisa M. (Cambridge University Press, 2012)
      Objective Early stress events severely impact brain and behaviour. From a neurobiological point of view early stress influences neuroanatomical structures and is associated with a dysregulation of the hypothalamic-pituit ...
    • Ortiz Contreras, Jovita; Paredes, Daniela; Neira Contreras, Rodrigo; Gálvez Ortega, Pablo Francisco (MedCrave, 2017)
      Epigenetics refers to the study of how genes express their phenotypic effect, all of which can be modified by the environment. Recently, pregnancy, labour and birth have been proposed as critical periods of exposure to ...
    • Guerrero-Bosagna, Calos M.; Sabat Kirkwood, Alejandro Pablo; Valdovinos, Fernanda S.; Valladares Boasi, Luis; Clark, Susan J. (BioMed Central, 2008-09-15)
      Background: Developmental effects of exposure to endocrine disruptors can influence adult characters in mammals, but could also have evolutionary consequences. The aim of this study was to simulate an environmental ...
    • Kokosar, Milana; Benrick, Anna; Perfilyev, Alexander; Fornes, Romina; Nilsson, Emma; Maliqueo Yevilao, Manuel; Behre, Carl Johan; Sazonova, Antonina; Ohlsson, Claes; Ling, Charlotte; Stener-Victorin, Elisabet (Nature Publishing Group, 2016)
      Genetic and epigenetic factors may predispose women to polycystic ovary syndrome (PCOS), a common heritable disorder of unclear etiology. Here we investigated differences in genome-wide gene expression and DNA methylation ...
    • Rojas, Adriana; Aguilar, Rodrigo; Henríquez, Berta; Lian, Jane B.; Stein, Janet L.; Stein, Gary S.; Wijnen, Andre J. van; Zundert, Brigitte van; Allende Connelly, Miguel; Montecino, Martín (The American Society for Biochemistry and Molecular Biology, 2015)
      Transcription factor Runx2 controls bone development and osteoblast differentiation by regulating expression of a significant number of bone-related target genes. Here, we report that transcriptional activation and repression ...
    • Carrillo Reixach, Juan; Torrens, Laura; Simon Coma, Marina; Royo, Laura; Domingo Sàbat, Montserrat; Abril Fornaguera, Jordi; Akers, Nicholas; Sala, Margarita; Ragull, Sonia; Arnal, Magdalena; Villalmanzo, Núria; Cairo, Stefano; Villanueva, Alberto; Kappler, Roland; Garrido, Marta; Guerra, Laura; Sábado, Constantino; Guillén, Gabriela; Mallo, Mar; Piñeyro, David; Vázquez Vitali, María; Kuchuk, Olga; Mateos, María Elena; Ramírez, Gema; López Santamaría, Manuel; Mozo, Yasmina; Soriano, Aroa; Grotzer, Michael; Branchereau, Sophie; García de Andoin, Nagore; López Ibor, Blanca; López Almaraz, Ricardo; Salinas, José Antonio; Torres, Bárbara; Hernández, Francisco; Uriz, José Javier; Fabre, Monique; Blanco, Julià; Paris Domínguez, Claudia; Bajčiová, Viera; Laureys, Geneviève; Masnou, Helena; Clos, Ariadna; Belendez, Cristina; Guettier, Catherine; Sumoy, Lauro; Planas, Ramón; Jordà, Mireia; Nonell, Lara; Czauderna, Piotr; Morland, Bruce; Sia, Daniela; Losic, Borjan; Buendia, Marie Annick; Sarrias, María Rosa; Llovet, Josep M.; Armengol, Carolina (Elsevier, 2020)
      Background & Aims: Hepatoblastoma (HB) is a rare disease. Nevertheless, it is the predominant pediatric liver cancer, with limited therapeutic options for patients with aggressive tumors. Herein, we aimed to uncover the ...
    • Loren, Pía; Saavedra, Nicolás; Saavedra, Kathleen; Zambrano Coloma, Tomas Andrés; Moriel, Patricia; Salazar, Luis A. (MDPI, 2021)
      Cisplatin is an antineoplastic drug used for the treatment of many solid tumors. Among its various side effects, nephrotoxicity is the most detrimental. In recent years, epigenetic regulation has emerged as a modulatory ...
    • Casanello, Paola; Herrera Videla, Emilio; Krause, Bernardo J. (INTECH, 2017)
      Most of the worldwide deaths in patients with non-communicable diseases are due to cardiovascular and metabolic diseases, which are determined by a mix of environmental, genetic and epigenetic factors, and by their ...
    • Kim, Soo Young; Zhang, Xin; Schiattarella, Gabriele G.; Altamirano, Francisco; Ramos, Thais; French, Kristin M.; Jiang, Nan; Szweda, Pamela A.; Evers, Bret M.; May, Herman; Luo, Xiang; Li, Hongliang; Szweda, Luke; Maracajá Coutinho, Vinicius; Lavandero González, Sergio; Gillette, Thomas G.; Hill, Joseph A. (Lippincott Williams & Wilkins, 2020)
      BACKGROUND: BET (bromodomain and extraterminal) epigenetic reader proteins, in particular BRD4 (bromodomain-containing protein 4), have emerged as potential therapeutic targets in a number of pathological conditions, ...
    • Piñuñuri Flores, Raúl; Castaño Moreno, Erika; Llanos Silva, Miguel; Ronco Macchiavello, Ana María (Elsevier, 2020)
      Introduction: Folates are essential nutrients for fetal development and pregnancy outcomes; they are transported to the fetus during gestation through specific folate transporters located in the placenta. In preterm newborns, ...