Browsing by Author "14b04a13-09ad-47ee-a904-d2876e61c9e9"

Now showing items 21-23 of 23

    • Trypanosoma cruzi calreticulin topographical variations in parasites infecting murine macrophages 
      González, Andrea; Valck, Carolina; Sánchez, Gittith; Härtel, Steffen; Mansilla, Jorge; Ramírez, Galia; Fernández, María Soledad; Arias, José; Galanti Garrone, Norbel; Ferreira, Arturo (American Society of Tropical Medicine and Hygiene, 2015)
      Trypanosoma cruzi calreticulin (TcCRT), a 47-kDa chaperone, translocates from the endoplasmic reticulum to the area of flagellum emergence. There, it binds to complement components C1 and mannan-binding lectin (MBL), thus ...
    • Trypanosoma cruzi calreticulin: A possible role in Chagas' disease autoimmunity 
      Hager Ribeiro, Carolina; López Bartolucci, Carolina; Ramírez Toloza, Galia; Valck Calderón, Carolina Eliana; Molina, María Carmen; Aguilar, Lorena; Rodríguez, Margarita; Maldonado, Ismael; Martínez, Ramón; González, Carlos; Troncoso Cotal, Rodrigo; Lavandero González, Sergio; Gingras, Alexandre R.; Schwaeble, Wilhelm; Ferreira, Arturo (PERGAMON-ELSEVIER SCIENCE LTD, 2009-03)
      Trypanosoma cruzi (T cruzi) is the causative agent of Chagas' disease, an endemic and chronic illness that affects 18 million people in Latin America. The mechanisms underlying its pathogenesis are controversial. There is ...
    • Variable numbers of calreticulin genes in Trypanosoma cruzi correlate with atypical morphology and protein ... 
      González, Andrea; Härtel, Steffen; Mansilla, Jorge; Sánchez-Valdéz, Fernando; Ferreira, Arturo (Elsevier GmbH, 2018)
      Trypanosoma cruzi calreticulin (TcCalr, formerly known as TcCRT), upon binding to Complement (C) C1 and ficolins, inhibits the classical and lectin pathways and promotes infectivity. This virulence correlates with the ...