Browsing by Author "201-0010781"
Now showing items 21-40 of 77
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Hernández Tapia, Sergio Guillermo (Universidad de Chile, 2008)El síndrome de ovario poliquístico (PCOS) es una patología neuroendocrina muy común en mujeres en edad fértil y está relacionada con más del 75% de los casos de infertilidad anovulatoria. Aunque la etiología del PCOS se ...
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Bahamondes Vidal, Gabriela Catalina (Universidad de Chile, 2011)La exposición al frío, activa los nervios simpáticos periféricos y aumenta la tasa de recambio de noradrenalina en órganos con inervación simpática. Este aumento de las concentraciones de noradrenalina en una madre gestante ...
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Parada Valderrama, Mirtha (Universidad de Chile, 2014)La planta Matico, Buddleja globosa Hope, Budlejaceae es una especie nativa en Chile de la cual se usan sus hojas por sus múltiples propiedades terapéuticas. Las investigaciones más recientes han permitido demostrar que el ...
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Ricu, Manuel A.; Ramirez, Victor D.; Paredes, Alfonso H.; Lara Peñaloza, Hernán (2012)Kisspeptin and its receptor GPR54 have been described as key hypothalamic components in the regulation of GnRH secretion. Kisspeptin is also present in several regions of the central nervous system and the peripheral organs ...
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Amweg, A. N.; Paredes, A.; Salvetti, N. R.; Lara Peñaloza, Hernán; Ortega, H. H. (Elsevier, 2011)Melanocortin receptors (MCRs) are involved in physiological responses to ACTH, as well as to -, - and -melanocytestimulating hormone ( -, - and -MSH). Their expression has previously been analyzed in various bovine ...
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Ricu, Manuel; Paredes, Alfonso; Greiner, Monika; Ojeda, Sergio R.; Lara Peñaloza, Hernán (2008)A substantial fraction of the noradrenergic innervation targeting the mammalian ovary is provided by neurons of the celiac ganglion. Although studies in the rat have shown that noradrenergic nerves reach the ovary near the ...
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Piquer, Beatriz; Fonseca, Jose L.; Lara Peñaloza, Hernán (BioScientifica Ltd., 2017)© 2017 Society for Reproduction and Fertility.Chronic cold stress produces adrenergic overload that can affect fetal development. The placental norepinephrine transporter (NET) clears norepinephrine (NE) from both maternal ...
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Lara Peñaloza, Hernán; McDonald, J. K.; Ahmed, C. E.; Ojeda, S. R. (1990)Immunosympathectomy produced by treatment of newborn rats with antibodies to nerve growth factor (NGF) delays ovarian development and disrupts estrous cyclicity. While these alterations have been ascribed to loss of ...
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Pikov, Víctor; Sridhar, Arun; Lara Peñaloza, Hernán (Frontiers Media SA, 2018-05-01)The polycystic ovary syndrome (PCOS) is the most prevalent ovarian pathology in women, with excessive sympathetic activity in the superior ovarian nerve (SON) playing an important role in inducing the PCOS symptoms in the ...
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Nugent, B. M.; Tobet, S. A.; Lara Peñaloza, Hernán; Lucion, A. B.; Wilson, M. E.; Recabarren, S. E.; Paredes, A. H. (2012)Hormones influence countless biological processes across an animal's lifespan. Many hormone-mediated events occur within developmental sensitive periods, during which hormones have the potential to cause permanent ...
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Riquelme, Raúl; Ruz, Freddy; Mayerhofer, Artur; Lara Peñaloza, Hernán (Wiley, 2020)Chronic cold stress affects ovarian morphology and impairs fertility in rats. It causes an ovarian polycystic ovary (PCOS)-like phenotype, which resembles PCOS in women. The mechanism of cold stress action involves increased ...
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Urra, Javier; Blohberger, Jan; Tiszavari, Michelle; Mayerhofer, Artur; Lara Peñaloza, Hernán (Nature, 2016)Growth and differentiation of ovarian follicles are regulated by systemic and local factors, which may include acetylcholine (ACh). Granulosa cells (GCs) of growing follicles and luteal cells produce ACh and in cultured ...
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In vivo blockade of ovarian sympathetic activity by neosaxitoxin prevents polycystic ovary in rats Campos, Miguel del; Lagos Wilson, Néstor; Lara Peñaloza, Hernán (Biocientífica, 2020)A high sympathetic tone is observed in the development and maintenance of the polycystic ovary (PCO) phenotype in rats. Neosaxitoxin (NeoSTX) specifically blocks neuronal voltage-dependent Na+ channels, and we studied ...
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Luna, S. L.; Neuman, S.; Aguilera, J.; Brown, D. I.; Lara Peñaloza, Hernán (2012)Increasing evidence in animal models and in humans shows that sympathetic nerve activity controls ovarian androgen biosynthesis and follicular development. Thus, sympathetic nerve activity participates in the follicular ...
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Lara Peñaloza, Hernán; Dissen, G. A.; Leyton Canales, Víctor; Paredes Vargas, Alfonso; Fuenzalida Cruz, Héctor; Fiedler Temer, Jenny; Ojeda, Sergio R. (ENDOCRINE SOC, 2000-03)A form of polycystic ovary (PCO) resembling some aspects of the human PCO syndrome can be induced in rats by a single injection of estradiol valerate (EV). An increase in sympathetic outflow to the ovary precedes, by several ...
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Lara Peñaloza, Hernán; Dissen, G. A.; Leyton Canales, Víctor; Paredes Vargas, Alfonso; Fuenzalida Cruz, Héctor; Fiedler Temer, Jenny; Ojeda, Sergio R. (ENDOCRINE SOC, 2000-03)A form of polycystic ovary (PCO) resembling some aspects of the human PCO syndrome can be induced in rats by a single injection of estradiol valerate (EV). An increase in sympathetic outflow to the ovary precedes, by several ...
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Acuña, Eric; Fornes, Romina; Fernandois, Daniela; Garrido, Maritza P.; Greiner, Monika; Lara Peñaloza, Hernán; Paredes, Alfonso H. (2009)Background: Depletion of ovarian follicles is associated with the end of reproductive function in ageing females. Recently, it has been described that this process parallels increases in the concentration of norepinephrine ...
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Sepúlveda, C. M.; Troncoso, C. C.; Lara Peñaloza, Hernán; Cárdenas, Ana María (ELSEVIER SCI IRELAND LTD, 1998-08-14)The effects of the increase of intracellular calcium, induced by membrane depolarization with 50 mM KCl, and arachidonic acid (AA) on the expression of 25-kD synaptosomal-associated protein (SNAP-25) were studied in cultured ...
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Dissen, G. A.; Lara Peñaloza, Hernán; Leyton Canales, Víctor; Paredes Vargas, Alfonso; Hill, D. F.; Costa, M. E.; Martínez Serrano, A.; Ojeda, Sergio R. (ENDOCRINE SOC, 2000-03)A single injection of estradiol valerate induces a form of cystic ovary resembling some aspects of the human polycystic ovarian syndrome. Preceding the development of follicular cysts, there is an increase in intraovarian ...
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Lara Peñaloza, Hernán; McDonald, John K.; Ojeda, Sergio R. (1990)The ovary is innervated by noradrenergic and peptidergic fibers. Treatment of neonatal rats with antibodies to nerve growth factor (NGF Ab) resulted in failure of the sympathetic (noradrenergic and neuropeptide-Y) nerves ...