Browsing by Author "201-0020935"
Now showing items 21-24 of 24
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Cordero Torres, Karina Lizzy; Espinoza Santander, Iris; Cáceres Lillo, Dante; Roco, Angela; Miranda Melo, Carla Soledad; Squicciarini Rueda, Valentina; Santander Gallo, Paula Andrea; Kuen Shiou, Lee; Saavedra Saavedra, Iván; Quiñones Sepúlveda, Luis (Spandidos Publications, 2010-05)Polycyclic aromatic hydrocarbons (PAHs) contained in tobacco smoke acquire carcinogenicity following their activation by xenobiotic-metabolizing enzymes to highly reactive metabolites. The cytochrome P4501A1 (CYP1A1) enzyme ...
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Quiñones Sepúlveda, Luis; Rosero P., Mario; Roco Arriagada, Angela Margarita; Moreno T., Iván; Sasso Aguirre, Jaime Alfredo; Varela Figueroa, Nelson; Cáceres Lillo, Dante; Saavedra Saavedra, Iván (Sociedad Médica de Santiago, 2008-10)Cytochrome P450 enzymes are very important to metabolize anti-carcinogenic agents. Therefore, understanding the role of these enzymes and their allele variants in the bioactivation or detoxification of drugs could greatiy ...
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Saavedra Saavedra, Iván; Tamayo Carrillo, Evelyn; Gamboa, A.; Sasso Aguirre, Jaime Alfredo; Varela Figueroa, Nelson; Moreno, Iván; Marchant Lavín, Dafne; Cáceres Lillo, Dante; Quiñones Sepúlveda, Luis (2010)Changes in bioavailability of anticonvulsant drugs such as topiramate may cause loss of or worsened seizure control. Thus, the purpose of this study was to evaluate, in a double-blind crossover design, the bioavailability ...
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Garay Cortesi, Joselyn Ivonne (Universidad de ChileCyberDocs, 2012)Los médicos prescriben fármacos sobre la base de sus características farmacológicas y sobre la posibilidad de obtener resultados clínicamente reproducibles. Sin embargo, muchos de los fármacos son eficaces en sólo 25% a ...