Browsing by Author "XX669162"
Now showing items 41-60 of 94
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Fernández, Virginia; Videla Cabrera, Luis (2009)Thyroid hormone (L-3,3′,5-triiodothyronine, T3) is important for the normal function of most tissues, with major actions on O2 consumption and metabolic rate. In the liver, these are due to (i) transcriptional activation ...
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Tapia, G.; Santibáñez, C.; Farías, J.; Fuenzalida, G.; Varela, P.; Videla Cabrera, Luis; Fernández Arancibia, Virginia (2010)We studied the role of Kupffer cell functioning in T3 liver preconditioning against ischemia–reperfusion (IR) injury using the macrophage inactivator gadolinium chloride (GdCl3) previous to T3 treatment. Male Sprague–Dawley ...
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Videla Cabrera, Luis (2010)
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Galleano, Mónica; Tapia Opazo, Gladys; Puntarulo, Susana; Varela, Patricia; Videla Cabrera, Luis; Fernández Arancibia, Virginia (Elsevier, 2011)Aims: Liver preconditioning against ischemia–reperfusion (IR) injury is a major area of experimental research, in which regulation of gene expression with cytoprotective responses due to transient oxidative stress development ...
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Soto Alarcón, Sandra A.; Valenzuela Báez, Rodrigo; Valenzuela Bonomo, Carlos; Videla Cabrera, Luis (Bentham Science Publ LTD, 2018)Background and Objective: The liver is an organ susceptible to a multitude of injuries that causes liver damage, like steatosis, non-alcoholic steatohepatitis, cirrhosis, hepatocellular carcinoma, and ischemia-reperfusion ...
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Echeverría González, Francisca; Ortiz, Macarena; Valenzuela Báez, Rodrigo; Videla Cabrera, Luis (Elsevier, 2016)Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that function as ligand-dependent transcription factors that can be activated by different types of fatty acids (FAs). Three isoforms of PPARs have ...
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Romanque U, Pamela; Uribe M, Mario; Videla Cabrera, Luis (2005)Ischemia-reperfusion (IR) liver injury is associated with temporary clamping of hepatoduodenal ligament during liver surgery, hypoperfusion shock and graft failure after liver transplantation. Mechanisms of IR liver injury ...
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Pettinelli, Paulina; Obregón, A. M.; Videla Cabrera, Luis (Grupo Aula Medica S.A., 2011)Nonalcoholic fatty liver disease (NAFLD) is the most important cause of chronic liver disease and is considered the hepatic manifestation of the metabolic syndrome associated with diabetes mellitus type 2. The prevalence ...
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Barrera, Cynthia; Valenzuela, Rodrigo; Rincón, Miguel Ángel; Espinosa, Alejandra; Echeverria, Francisca; Romero, Nalda; Gonzalez-Mañan, Daniel; Videla Cabrera, Luis (Elsevier Inc., 2018)© 2018 Elsevier Inc. Enhanced iron levels in liver are associated with oxidative stress development and damage with increased fat accumulation. The aim of this work was to assess the hypothesis that antioxidant-rich extra ...
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Valenzuela, Rodrigo; Espinosa, Alejandra; González Mañán, Daniel Alonso; D'Espessailles Tapia, Amanda; Fernández Arancibia, Virginia; Videla Cabrera, Luis; Tapia Opazo, Gladys (2012)Omega-3 (n-3) long-chain polyunsaturated fatty acids (n-3 LCPUFA) are associated with several physiological functions, suggesting that their administration may prevent non transmissible chronic diseases. Therefore, we ...
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Tapia Opazo, Gladys; Valenzuela Báez, Rodrigo; Espinosa Escalona, Berta; Romanque Ulloa, Pamela; Dossi Muñoz, Camila; González Mañán, Daniel Alonso; Videla Cabrera, Luis; D'Espessailles Tapia, Amanda (WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim, 2014)Scope: Dietary n-3 long-chain PUFAs (n-3 LCPUFAs) supplementation was studied in an HFD-induced (HFD is high-fat diet) steatosis and inflammation in relation to peroxisome proliferator-activated receptor alpha (PPAR- ) ...
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Tapia Opazo, Gladys; Valenzuela, Rodrigo; Espinosa, Alejandra; Romanque, Pamela; Dossi, Camila; González Mañán, Daniel Alonso; Videla Cabrera, Luis; D'Espessailles Tapia, Amanda (Wiley-VCH Verlag, 2014)Scope: Dietary n-3 long-chain PUFAs (n-3 LCPUFAs) supplementation was studied in an HFD-induced (HFD is high-fat diet) steatosis and inflammation in relation to peroxisome proliferator-activated receptor alpha (PPAR-α) and ...
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Zúñiga, Jessica; Cancino, Milena; Medina, Fernando; Varela, Patricia; Vargas, Romina; Tapia Opazo, Gladys; Videla Cabrera, Luis; Fernández Arancibia, Virginia (2011)Dietary supplementation with the n-3 polyunsaturated fatty acids (n-3 PUFA) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) to rats preconditions the liver against ischemia-reperfusion (IR) injury, with reduction ...
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Morales, Paula; Vargas, Romina; Videla Cabrera, Luis; Fernández Arancibia, Virginia (2014)Sub-chronic iron (Fe) administration induces liver oxidative stress upregulating cytoprotective mechanisms that may involve redox-sensitive nuclear factor erythroid 2-related factor 2 (Nrf2). We aimed to investigate whether ...
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Valenzuela, Rodrigo; Das, Undurti N.; Videla Cabrera, Luis; Llorente, Carolina G. (Hindawi, 2018)
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Thielemann, L. E.; Rodrigo Salinas, Ramón; Oberhauser, E. W.; Rosenblut, G.; Videla Cabrera, Luis (1995)The role of regenerative processes in the protective effect of N‐acetyl‐L‐cysteine (NAC) against bromoethylamine‐induced renal papillary necrosis was assessed in rats given bromoethylamine (BEA) (1.2 mmol/kg), N‐acetylcysteine ...
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Fernández, Virginia; Videla Cabrera, Luis (1995)Administration of single doses of 0.1 mg L-triiodothyronine (T3)/kg for 3 consecutive days to fed rats produced a drastic increase in the respiratory burst activity of isolated polymorphonuclear leukocytes (PMN), stimulated ...
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Videla Cabrera, Luis; Rodrigo Salinas, Ramón; Araya, Julia; Poniachik Teller, Jaime (PERGAMON-ELSEVIER SCIENCE LTD, 2004-11-01)Human nonalcoholic fatty liver disease (NAFLD) associated with obesity is characterized by depletion of hepatic n-3 long-chain polyunsaturated fatty acids (LCPUFA), with lower LCPUFA product/precursor ratios and higher ...
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Videla Cabrera, Luis; Rodrigo Salinas, Ramón; Orellana Bown, Myriam; Fernandez, Virginia; Tapia Opazo, Gladys; Quiñones Sepúlveda, Luis; Varela Figueroa, Nelson; Contreras, Jorge; Lazarte, Raúl; Csendes Juhasz, Attila; Rojas Caro, Jorge; Maluenda, Fernando; Burdiles Pinto, Patricio; Díaz Jeraldo, Juan; Smok Sahid, Gladys; Thielemann, Lilian; Poniachik Teller, Jaime (Clinical Science, 2004-03)Oxidative stress is implicated in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). In the present study, hepatic and plasma oxidative stress-related parameters were measured and correlated with clinical and ...
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Calderón, Frances H.; Bonnefont, Andrea; Muñoz, Francisco J.; Fernández, Virginia; Videla Cabrera, Luis; Inestrosa, Nibaldo C. (1999)This work addresses the differential effects of several oxidative insults on two neuronal cell lines, PC12 and Neuro 2a cells, extensively used as neuronal models in vitro. We measured cellular damage using the cytotoxic ...