Browsing by Author "155f5579-5a6d-4c00-aa43-16c32d48dee9"

Now showing items 1-10 of 10

    • ACE2 and vasoactive peptides: Novel players in cardiovascular/renal remodeling and hypertension 
      Mendoza Torres, Evelyn; Oyarzún, Alejandra; Mondaca Ruff, David; Azocar, Andrés; Chiong Lay, Mario; Castro, Pablo F.; Jalil Milad, Jorge; Lavandero González, Sergio; Ocaranza, María Paz (2015)
      The renin–angiotensin system (RAS) is a key component of cardiovascular physiology and homeostasis due to its influence on the regulation of electrolyte balance, blood pressure, vascular tone and cardiovascular remodeling. ...
    • Angiotensin-(1-9) reduces cardiovascular and renal inflammation in experimental renin-independent hypertension 
      González, Leticia; Novoa, Ulises; Moya, Jackeline; Gabrielli, Luigi; Jalil Milad, Jorge; García Nannig, Lorena; Chiong Lay, Mario; Lavandero González, Sergio; Ocaranza, María Paz (Elsevier Inc., 2018)
      © 2018 Elsevier Inc. Hypertension-induced cardiovascular and renal damage can be mediated by activation of the renin-angiotensin-aldosterone system. There are different factors beyond renin-angiotensin-aldosterone system ...
    • Angiotensin-(1-9) regulates cardiac hypertrophy in vivo and in vitro 
      Ocaranza, Maria Paz; Lavandero González, Sergio; Jalil Milad, Jorge; Moya, Jaqueline; Pinto, Melissa; Novoa, Ulises; Apablaza, Felipe; González, Leticia; Hernández, Carol; Varas, Manuel; López, René; Godoy, Iván; Verdejo, Hugo; Chiong Lay, Mario (Lippincott Williams and Wilkins, 2010)
      Background: Angiotensin-(1-9) is present in human and rat plasma and its circulating levels increased early after myocardial infarction or in animals treated with angiotensin-converting enzyme inhibitor. However, the ...
    • Changes in cyclic AMP dependent protein kinase and active stiffness in the rat volume overload model of ... 
      Lavandero González, Sergio; Cartagena, Gastón; Guarda, Eduardo; Corbalán, Ramón; Godoy, Iván; Sapag Hagar, Mario; Jalil Milad, Jorge (Oxford University Press, 1993)
      Objective: The aim was to clarify the role of cyclic AMP dependent protein kinase (PKA) and changes in mechanical heart function during development of cardiac hypertrophy induced by volume overload. Methods: Protein and ...
    • Cyclic AMP-dependent protein kinase and mechanical heart function in ventricular hypertrophy induced by ... 
      Piddo Mijares, Ana María; Sánchez, María Isabel; Sapag Hagar, Mario; Corbalán, Ramón; Foncea, Rocío; Ebensperger González, Roberto; Godoy, Iván; Meléndez, Jaime; Jalil Milad, Jorge; Lavandero González, Sergio (Academic Press, 1996)
      The role of cyclic AMP-dependent protein kinase (PKA) and systolic function during the development of left ventricular hypertrophy (LVH) still remain uncertain. The aim of this work is to study PKA activity and mechanical ...
    • Perindopril regulates β-agonist-induced cardiac apoptosis 
      Gálvez, Anita S.; Fiedler Temer, Jenny; Ocaranza, María Paz; Jalil Milad, Jorge; Lavandero González, Sergio; Díaz Araya, Guillermo (2005)
      Administration of the β-adrenergic agonist isoproterenol results in cardiac apoptosis, The effect of short-term β-adrenergic stimulation by isoproterenol on the activity of plasma, lung, and left ventricular (LV) angiotensin ...
    • Prevalence of the angiotensin I converting enzyme insertion/deletion polymorphism, plasma angiotensin ... 
      Jalil Milad, Jorge; Piddo, Ana María; Cordova, Samuel; Chamorro, Gastón; Braun, Sandra; Jalil, Roberto; Vega, Jeanette; Jadue, Liliana; Lavandero González, Sergio; Lastra, Patricia (1999)
      The aim of this study was to estimate the prevalence of the different alleles of the angiotensin converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism and associated plasma ACE activity, as well as cardiac ...
    • Protection of the myocardium against ischemia/reperfusion injury by angiotensin-(1–9) through an AT2R and ... 
      Mendoza Torres, Evelyn; Riquelme, Jaime A.; Vielma, Alejandra; Sagredo, Andrea Ramirez; Gabrielli, Luigi; Bravo Sagua, Roberto; Jalil Milad, Jorge; Rothermel, Beverly A.; Sánchez, Gina; Ocaranza, María Paz; Lavandero González, Sergio (Academic Press, 2018)
      © 2018 Elsevier Ltd Angiotensin-(19), a peptide of the non-classical renin angiotensin system, has been shown to prevent and revert hypertension and cardiac hypertrophy. We hypothetized that systemic delivery of angiotensin-(1–9) ...
    • Reply: Dissociating angiotensin 1-9 anticardiovascular remodeling effects from those on blood pressure 
      Ocaranza, María Paz; Michea Acevedo, Luis; Chiong Lay, Mario; Lavandero González, Sergio; Jalil Milad, Jorge (Lippincott Williams and Wilkins, 2014)
    • Selective increase in cardiac IGF-1 in a rat model of ventricular hypertrophy 
      Ebensperger González, Roberto; Acevedo, Erika; Meléndez, Jaime; Corbalán, Ramón; Acevedo, Mónica; Sapag Hagar, Mario; Jalil Milad, Jorge; Lavandero González, Sergio (Academic Press Inc., 1998)
      There is evidence that insulin-like growth factor-1 (IGF-1) plays a role in the development of left ventricular hypertrophy, but it is uncertain whether cardiac IGP-1 changes before or after hypertension is established, ...