Browsing by Author "García Beltrán, Olimpo José"

Now showing items 1-3 of 3

    • Coumarin-chalcone hybrids as inhibitors of MAO-B: Biological activity and in silico studies 
      Moya Alvarado, Guillermo Adrian; Yáñez, Osvaldo; Morales, Nicole; González González, Angélica; Areche Medina, Carlos Alberto; Núñez González, Marco Tulio; Fierro, Angélica; García Beltrán, Olimpo José (MDPI, 2021)
      Fourteen coumarin-derived compounds modified at the C3 carbon of coumarin with an alpha,beta-unsaturated ketone were synthesized. These compounds may be designated as chalcocoumarins (3-cinnamoyl-2H-chromen-2-ones). Both ...
    • In silico study of coumarins and quinolines derivatives as potent inhibitors of sars-cov-2 main protease 
      Yáñez, Osvaldo; Osorio, Manuel Isaías; Uriarte, Eugenio; Areche Medina, Carlos Alberto; Tiznado, William; Pérez Donoso, José M.; García Beltrán, Olimpo José; González Nilo, Fernando Danilo (Frontiers Media, 2021)
      The pandemic that started in Wuhan (China) in 2019 has caused a large number of deaths, and infected people around the world due to the absence of effective therapy against coronavirus 2 of the severe acute respiratory ...
    • Theobroma cacao L. compounds: Theoretical study and molecular modeling as inhibitors of main SARS-CoV-2 protease 
      Yáñez Osses, Osvaldo Andrés; Osorio, Manuel Isaías; Areche Medina, Carlos Alberto; Vásquez Espinal, Alejandro; Bravo, Jéssica; Sandoval Aldana, Angélica; Pérez Donoso, José M.; González Nilo, Fernando Danilo; Matos, María Joao; Osorio, Edison; García Beltrán, Olimpo José; Tiznado Vásquez, William Artemio (Elsevier, 2021)
      Cocoa beans contain antioxidant molecules with the potential to inhibit type 2 coronavirus (SARS-CoV-2), which causes a severe acute respiratory syndrome (COVID-19). In particular, protease. Therefore, using in silico ...