Browsing by Author "Henríquez, Daniel R."

Now showing items 1-5 of 5

    • A feed-forward mechanism involving the NOX complex and RyR-mediated Ca2 release during axonal specification 
      Wilson, Carlos; Muñoz Palma, Ernesto; Henríquez, Daniel R.; Palmisano, Ilaria; Núñez González, Marco; Di Giovanni, Simone; González Billault, Christian (Soc Neuroscience, 2016)
      Physiological levels of ROS support neurite outgrowth and axonal specification, but the mechanisms by which ROS are able to shape neurons remain unknown. Ca2+, a broad intracellular second messenger, promotes both Rac1 ...
    • Cdk5 regulates Rap1 activity 
      Utreras Puratich, Elías; Henríquez, Daniel R.; Contreras Vallejos, Erick; Olmos, Cristina; Di Genova, Alex; Maass Sepúlveda, Alejandro; Kulkarni, Ashok B.; González Billault, Christian (2013)
      Rap1 signaling is important for migration, differentiation, axonal growth, and during neuronal polarity. Rap1 can be activated by external stimuli, which in turn regulates specific guanine nucleotide exchange factors such ...
    • Crosslinking and mass spectrometry suggest that the isolated NTD domain dimer of Moloney murine leukemia ... 
      Henríquez, Daniel R.; Zhao, Caifeng; Zheng, Haiyan; Arbildua, José J.; Acevedo Acevedo, Mónica; Roth, Monica J.; León Decap, Oscar (2013)
      Background: Retroviral integrases (INs) catalyze the integration of viral DNA in the chromosomal DNA of the infected cell. This reaction requires the multimerization of IN to coordinate a nucleophilic attack of the 3’ ...
    • Exchange Protein Directly Activated by cAMP (EPAC) Regulates Neuronal Polarization through Rap1B 
      Muñoz Llancao, Pablo; Henríquez, Daniel R.; Wilson, Carlos; Bodaleo, Felipe; Boddeke, Erik W.; Lezoualc'h, Frank; Schmidt, Martina; González Billault, Christian (Soc. Neuroscience, 2015)
      Acquisition of neuronal polarity is a complex process involving cellular and molecular events. The second messenger cAMP is involved in axonal specification through activation of protein kinase A. However, an alternative ...
    • The role of small GTPases in neuronal morphogenesis and polarity 
      González Billault, Christian; Muñoz Llancao, Pablo; Henríquez, Daniel R.; Wojnacki, José; Conde, Cecilia; Cáceres, Alfredo (2012)
      The highly dynamic remodeling and cross talk of the microtubule and actin cytoskeleton support neuronal morphogenesis. Small RhoGTPases family members have emerged as crucial regulators of cytoskeletal dynamics. In this ...