Browsing by Author "López, Nandy"

Now showing items 1-3 of 3

    • Extracellular Trypanosoma cruzi calreticulin in the host-parasite interplay 
      Ramírez Toloza, Galia; Valck, Carolina; Ferreira, Viviana P.; López, Nandy; Ferreira Vigouroux, Luis Arturo (Elsevier, 2011-03)
      Calreticulin (CRT) from vertebrates is a calcium-binding protein present mainly in the endoplasmic reticulum (ER). There, it directs the conformation of proteins and controls calcium levels. This review will focus on several ...
    • Molecular mechanisms involved in the inactivation of the first component of human complement by Trypanosoma ... 
      Valck, Carolina; Ramírez Toloza, Galia; López, Nandy; Ribeiro, Carolina Hager; Maldonado, Ismael; Sánchez, Gittith; Ferreira, Viviana; Schwaeble, Wilhelm; Ferreira Vigouroux, Luis Arturo (ELSEVIER, 2010)
      Trypanosoma cruzi (T. cruzi), the agent of Chagas’ disease, the sixth most important neglected tropical disease worldwide, causes 50,000 deaths per year in Latin America. T. cruzi calreticulin (TcCRT), a highly pleiotropic ...
    • Trypanosoma cruzi calreticulin: A novel virulence factor that binds complement C1 on the parasite surface ... 
      Ramírez Toloza, Galia; Valck, Carolina; Molina, María C.; Ribeiro, Carolina Hager; López, Nandy; Sánchez, Gittith; Ferreira, Viviana P.; Billetta, Rosario; Aguilar, Lorena; Maldonado, Ismael; Cattan Ayala, Pedro; Schwaeble, Wilhelm; Ferreira Vigouroux, Luis Arturo (Elsevier, 2011)
      In Trypanosoma cruzi, calreticulin (TcCRT) translocates from the endoplasmic reticulum (ER) to the area of flagellum emergence. We propose herein that the parasite uses this molecule to capture complement C1, in an ...