Browsing by Author "Lourido, Fernanda"

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    • Mitochondrial iron homeostasis and its dysfunctions in neurodegenerative disorders 
      Mena, Natalia P.; Urrutia, Pamela J.; Lourido, Fernanda; Carrasco, Carlos M.; Núñez González, Marco (Elsevier, 2015)
      Synthesis of the iron-containing prosthetic groups—heme and iron–sulfur clusters—occurs in mitochondria. The mitochondrion is also an important producer of reactive oxygen species (ROS), which are derived fromelectrons leaking ...
    • The novel mitochondrial iron chelator 5-((methylamino)methyl)-8-hydroxyquinoline protects against ... 
      Mena, Natalia P.; García Beltrán, Olimpo; Lourido, Fernanda; Urrutia, Pamela J.; Mena, Raúl; Castro Castillo, Vicente; Cassels Niven, Bruce; Núñez González, Marco (Elsevier, 2015)
      Abundant evidence indicates that iron accumulation, oxidative damage and mitochondrial dysfunction are common features of Huntington's disease, Parkinson's disease, Friedreich's ataxia and a group of disorders known as ...