Browsing by Author "Maldonado, Paula"

Now showing items 1-4 of 4

    • Alloreactive Regulatory T Cells Allow the Generation of Mixed Chimerism and Transplant Tolerance 
      Ruiz, Paulina; Maldonado, Paula; Hidalgo, Yessia; Sauma Mahaluf, Daniela; Rosemblatt Silber, Mario César; Bono Merino, María Rosa (Frontiers Media, 2015)
      The induction of donor-specific transplant tolerance is one of the main goals of modern immunology. Establishment of a mixed chimerism state in the transplant recipient has proven to be a suitable strategy for the induction ...
    • Alloreactive regulatory T cells generated with retinoic acid prevent skin allograft rejection 
      Moore, Carolina; Tejón, Gabriela; Fuentes, Camila; Hidalgo, Yessia; Bono Merino, María Rosa; Maldonado, Paula; Fernández, Ricardo; Wood, Kathryn; Fierro, Juan; Rosemblatt Silber, Mario César; Sauma Mahaluf, Daniela; Bushell, Andrew (Wiley-Blackwell, 2015)
      CD4+CD25+Foxp3+ regulatory T (Treg) cells mediate immunological self-tolerance and suppress immune responses. Retinoic acid (RA), a natural metabolite of vitamin A, has been reported to enhance the differentiation of ...
    • T helper type 17 cells contribute to anti-tumour immunity and promote the recruitment of T helper type 1 ... 
      Nuñez, Sarah; Saez, Juan José; Fernández, Dominique; Flores Santibañez, Felipe; Álvarez, Karla; Tejón, Gabriela; Ruiz, Paulina; Maldonado, Paula; Hidalgo, Yessia; Manriquez, Valeria; Bono Merino, María Rosa; Rosemblatt Silber, Mario César; Sauma Mahaluf, Daniela (Blackwell Publishing, 2013)
      T helper type 17 (Th17) lymphocytes are found in high frequency in tumour-burdened animals and cancer patients. These lymphocytes, characterized by the production of interleukin-17 and other pro-inflammatory cytokines, ...
    • Transplant Tolerance: New Insights and Strategies for Long-Term Allograft Acceptance 
      Ruiz, Paulina; Maldonado, Paula; Hidalgo, Yessia; Gleisner, Alejandra; Sauma Mahaluf, Daniela; Silva, Cinthia; Saez, Juan José; Nuñez, Sarah; Rosemblatt Silber, Mario César; Bono Merino, María Rosa (Hindawi, 2013)
      One of the greatest advances in medicine during the past century is the introduction of organ transplantation. This therapeutic strategy designed to treat organ failure and organ dysfunction allows to prolong the survival ...