Browsing by Author "Pérez, Viviana"

Now showing items 1-5 of 5

    • ALS-linked protein disulfide isomerase variants cause motor dysfunction 
      Woehlbier, Ute; Colombo Flores, Alicia; Saaranen, Mirva J.; Pérez, Viviana; Ojeda, Jorge; Bustos, Fernando J.; Andreu, Catherine; Torres, Mauricio; Valenzuela, Vicente; Medinas Bilches, Danilo; Rozas, Pablo; Vidal, René L.; López González, Rodrigo; Salameh, Johnny; Fernández Collemann, Sara; Muñoz, Natalia; Matus, Soledad; Armisen Yáñez, Ricardo; Sagredo, Alfredo; Palma, Karina; Irrázabal, Thergiory; Almeida, Sandra; González Pérez, Paloma; Campero, Mario; Gao, Fen-Biao; Henny, Pablo; Van Zundert, Brigitte; Ruddock, Lloyd W.; Concha, Miguel L.; Henríquez, Juan P.; Brown, Robert H.; Hetz Flores, Claudio (Wiley-Blackwell, 2016)
      Disturbance of endoplasmic reticulum (ER) proteostasis is a common feature of amyotrophic lateral sclerosis (ALS). Protein disulfide isomerases (PDIs) are ER foldases identified as possible ALS biomarkers, as well as ...
    • Mitochondrial dysfunction and the glycolytic switch induced by caveolin-1 phosphorylation promote cancer ... 
      Díaz Valdivia, Natalia; Simón, Layla; Díaz, Jorge; Martínez Meza, Samuel; López Contreras, Pamela; Burgos Ravanal, Renato; Pérez, Viviana; Frei, Balz; Leyton Campos, Lisette; Quest, Andrew Frederick Geoffery (MDPI, 2022)
      Simple Summary Caveolin-1 (CAV1) is a membrane protein that has been attributed a dual role in cancer, acting at early stages as a tumor suppressor and in later stages of the disease as a promoter of metastasis. In the ...
    • Protein disulfide isomerase ERp57 protects early muscle denervation in experimental ALS 
      Rozas Rojas, Pablo Sebastián; Pinto, Cristina; Martínez Traub, Francisca José; Díaz Hinojosa, Rodrigo Ignacio; Pérez, Viviana; Becerra, Daniela; Ojeda, Patricia; Ojeda, Jorge; Wright, Madison T.; Mella, Jéssica; Plate, Lars; Henríquez, Juan Pablo; Hetz Flores, Claudio Andrés; Bilches Medinas, Danilo (BMC, 2021)
      Amyotrophic lateral sclerosis (ALS) is a progressive fatal neurodegenerative disease that affects motoneurons. Mutations in superoxide dismutase 1 (SOD1) have been described as a causative genetic factor for ALS. Mice ...
    • Serum from aged F344 rats conditions the activation of young macrophages 
      Gómez, Christian; Acuña Castillo, Claudio; Nishimura, Sumiyo; Pérez, Viviana; Escobar, Alejandro; Salazar Onfray, Flavio; Sabaj Diez, Valeria; Torres, Claudio; Walter, Robin Ann; Sierra, Felipe (ELSEVIER, 2006-03)
      There is considerable controversy about the molecular mechanisms responsible for the variations in innate immunity associated with age. While in vivo, aged animals and humans react to an inflammatory signal with ail excessive ...
    • T-kininogen induces endothelial cell proliferation 
      Pérez, Viviana; Leiva Salcedo, Elías; Acuña Castillo, Claudio; Aravena, Mauricio; Gómez, Christian; Sabaj Diez, Valeria; Colombo, Alicia; Nishimura, Sumiyo; Pérez Núñez, Claudio; Walter, Robin Ann; Sierra, Felipe (ELSEVIER, 2006-03)
      Basal proliferation of endothelial cells increases with age, and this might play a role in the etiology of age-related vascular diseases, as well as angiogenesis. Serum kininogen levels increase during aging in rats and ...