Browsing by Author "Parsons, Geoffrey"

Now showing items 1-2 of 2

    • Activation of the unfolded protein response promotes axonal regeneration after peripheral nerve injury 
      Oñate, Martiza; Catenaccio, Alejandra; Martínez, Gabriela; Armentano, Donna; Parsons, Geoffrey; Kerr, Bredford; Hetz Flores, Claudio; Court, Felipe (Nature Publishing Group, 2016)
      Although protein-folding stress at the endoplasmic reticulum (ER) is emerging as a driver of neuronal dysfunction in models of spinal cord injury and neurodegeneration, the contribution of this pathway to peripheral nerve ...
    • Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1 
      Valdés, Pamela; Mercado, Gabriela; Vidal, René L.; Molina, Claudia; Parsons, Geoffrey; Court, Felipe A.; Martínez, Alexis; Galleguillos, Danny; Armentano, Donna; Schneider, Bernard L.; Hetz Flores, Claudio (CrossMark, 2014)
      Parkinson disease (PD) is characterized by the selective loss of dopaminergic neurons of the substantia nigra pars compacta (SNpc). Although growing evidence indicates that endoplasmic reticulum (ER) stress is a hallmark ...