Browsing by Author "Reyes, José Miguel"

Now showing items 1-7 of 7

    • Absence of CHEK2 1100delC mutation in familial breast cancer cases from a South American population 
      González Hormazábal, Patricio; Castro, Víctor G.; Blanco Castillo, Rafael; Gómez, Fernando; Peralta Musre, Octavio; Waugh, Enrique; Bravo, Teresa; Reyes, José Miguel; Jara Sosa, Lilian (SPRINGER, 2008-08)
    • Association of common ATM variants with familial breast cancer in a South American population 
      González Hormazábal, Patricio; Bravo, Teresa; Blanco Castillo, Rafael; Valenzuela, Carlos Y.; Gómez, Fernando; Waugh, Enrique; Peralta Musre, Octavio; Ortúzar, Waldo; Reyes, José Miguel; Jara Sosa, Lilian (BIOMED CENTRAL LTD, 2008-04-23)
      Background: The ATM gene has been frequently involved in hereditary breast cancer as a low-penetrance susceptibility gene but evidence regarding the role of ATM as a breast cancer susceptibility gene has been contradicto ...
    • BRCA1 and BRCA2 mutations in a South American population 
      Jara Sosa, Lilian; Ampuero Llanos, Sandra; Santibáñez, Eudocia; Seccia, Lorena; Rodríguez, Juan; Bustamante, Mario; Martínez, Víctor; Catenaccio, Alejandra; Lay-Son, Guillermo; Blanco Castillo, Rafael; Reyes, José Miguel (ELSEVIER, 2006-04-01)
      A sample of 64 high-risk breast and/or ovarian cancer families from Chile were screened for germline mutations in the coding sequences and exon-intron boundaries of BRCA1 (MIN no. 113705) and BRCA2 (MIN no. 600185) genes ...
    • Genetic variation in MicroRNA-423 promotes proliferation, migration, invasion, and chemoresistance in breast ... 
      Morales Pisón, Sebastián; Jara Sosa, Lilian Elena Jonasa; Carrasco, Valentina; Gutiérrez Vera, Cristian Alfonso; Reyes, José Miguel; González Hormazábal, Sebastián Patricio; Carreño Márquez, Leandro Javier; Tapia Pineda, Julio César; Contreras Muñoz, Héctor Ruberly (MDPI, 2022)
      MicroRNA-423 (miR-423) is highly expressed in breast cancer (BC). Previously, our group showed that the SNP rs6505162:C>A located in the pre-miR-423 was significantly associated with increased familial BC risk in patients ...
    • Heritable genomic diversity in breast cancer driver genes and associations with risk in a chilean population 
      Morales Pison, Sebastián Felipe; González Hormazábal, Patricio Andrés; Tapia Pineda, Julio César; Salas Burgos, Alexis Marcelo; Ampuero Llanos, Sandra Patricia; Gómez, Fernando; Waugh, Enrique; Reyes, José Miguel; Jara Sosa, Lilian Elena Jonasa (BMC, 2022)
      Background Driver mutations are the genetic components responsible for tumor initiation and progression. These variants, which may be inherited, influence cancer risk and therefore underlie many familial cancers. The present ...
    • Manejo paliativo del cáncer de vesícular biliar irresecable o metastásico: conclusiones del Consenso ... 
      Müller, Bettina; Arroyo, Gerardo; Gallardo, Jorge; Villanueva Olivares, Luis; González, Pablo; Baeza, Ramón; Aretxabala, Xabier de; Maluenda, Fernando; Acevedo, Alejandro; Chuecas, Fernando; Díaz Jeraldo, Juan; García S., César; Reyes, José Miguel; Navarrete, Claudio (Sociedad Médica de Santiago, 2011-02)
    • Mutational landscape and actionable target rates on advanced stage refractory cancer patients: a multicenter ... 
      Córdova Delgado, Miguel Angel; Pinto, Mauricio P.; Regonesi, Carlos; Cereceda, Luis; Reyes, José Miguel; Itriago, Laura; Majlis, Alejandro; Rodríguez, Pablo; Fassler, André; Mahave, Mauricio; León, María Elisa; Gallardo, Jorge; Rodríguez Z., María Paz; Berkovits, Alejandro; Manque, Patricio; Ríos, Juvenal A.; García Bloj, Benjamín; Garrido, Marcelo (MDPI, 2022)
      Major advances in sequencing technologies and targeted therapies have accelerated the incorporation of oncology into the era of precision medicine and "biomarker-driven" treatments. However, the impact of this approach on ...