Browsing by Author "Segura-Aguilar, Juan"
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Castillo González, Sebastián (2015)La epigenética como ciencia se dedica al estudio de la regulación de la transcripción de genes determinados, que está dada sin alteración en la secuencia de las bases nitrogenadas, siendo esta regulación marcas mitótica y ...
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Novel Alpha-Synuclein Oligomers Formed with the Aminochrome-Glutathione Conjugate Are Not Neurotoxic Huenchuguala, Sandro; Sjödin, Birgitta; Mannervik, Bengt; Segura-Aguilar, Juan (Springer New York LLC, 2019)© 2018, Springer Science+Business Media, LLC, part of Springer Nature.Aminochrome induces neurotoxic alpha-synuclein oligomer formation relevant to the etiology of Parkinson’s disease. Oxidative stress produces aminochrome ...
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Segura-Aguilar, Juan (Elsevier Ltd, 2019)One of the major problems in the translation of successful preclinical results to clinical studies and new therapies in Parkinson's disease is the use of preclinical models based on exogenous neurotoxins that do not replicate ...