Browsing by Author "Sepúlveda Boza, Silvia"
Now showing items 1-17 of 17
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Osorio Olivares, Mauricio; Caroli Rezende, Marcos; Sepúlveda Boza, Silvia; Cassels Niven, Bruce; Baggio, Ricardo; Muñoz Acevedo, Juan Carlos (Elsevier Science Ltd., 2003-03-12)Abstract—A simple method for the preparation of homochiral ring-substituted 1-aryl-2-aminopropanones 2 (‘cathinones’) is described, involving initial Friedel–Crafts acylation of aromatics with (S)- or (R)-N-trifluoroacetylalanyl ...
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Cassels Niven, Bruce; Sepúlveda Boza, Silvia (Sociedad Chilena de Química, 1990-04-16)La bromación del 2,5-dimetoxibenzaldehído en ácido acético dió 4-bromo2,5- dimetoxi-y 2-bromo-3,6-dimetoxibenzaldehído en una razón de 4:1. El primero de éstos sufrió sustituciones nucleofilicas con tioles en DMF ...
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Sepúlveda Boza, Silvia; Cassels Niven, Bruce (Laboratorios Mixim, S.A., 1979)SOJlhork'".ide .,..1 \-al.led In 2,3~ yi.ld 'rom IlI&Vft 01 SclliIJIIS I.,jfoUlIs (An.c.rdl.c •• e), used u a lolk ~unlr.~épliv,. Thi. compoulld mi)' be relpon.lblc '01 Ihe plent', .ttrlhuted llltif,nill1y pmpel1lí1,
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Sepúlveda Boza, Silvia; Delhvi, Sualaheen; Cassels Niven, Bruce (Pergamon Press, 1989-09-06)The stem bark of Persea lingue afforded a new aryltetralin lignan, named lingueresinol, which was shown to be a positional isomer of epi-lyoniresinol.
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Sepúlveda Boza, Silvia; Delhvi, Sualaheen; Koch, B.; Zilliken, Federico; Cassels Niven, Bruce (Elsevier , Science Ltd., 1992-11-02)
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Mejías, Lorenzo; Caroli Rezende, Marcos; Sepúlveda Boza, Silvia; Araya Maturana, Ramiro; Boys Mardones, Daphne; Cassels Niven, Bruce; Manríquez Castro, Víctor (SOCIEDAD CHILENA DE QUIMICA, 1998-12)An X-ray diffraction study of the 7-bromo-5,8-dihydroxy-4,4-dimethyl-4H-naphthalen--1-one (1), obtained by bromination of 5,8-dihydroxy-4.4-dimethyl-4H-naphthalen-1-one with molecular bromine, gave unambiguous proof of its ...
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Conceição Silva, Antonio J.G.; Giotto, Maria T.S.; Mascarenhas, Yvonne P.; Sepúlveda Boza, Silvia; Cassels Niven, Bruce (Sociedad Chilena de Quimica, 1999)The crystal and molecular structures of (E)-1-(3,4,5-trimethoxyphenyl)-2-nitroethene (1), C11H13NO5, Mr = 239.2, and (E)-1-(3,4,5-trimethoxyphenyl)-2-nitropropene (2), C12H15NO5, Mr = 253.3, were determined by X-ray ...
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Zapata Torres, Gerald Amilcar; Opazo, Felipe; Salgado, J. Cristián; Muñoz Concha, Juan; Krautwurst, Hans; Mascayano, Carolina; Sepúlveda Boza, Silvia; Maccioni Baraona, Ricardo; Cassels Niven, Bruce (AMER CHEMICAL SOC, 2004-03)A number of natural and synthetic flavonoids have been assessed previously with regard to their effects on the activity of cyclin-dependent kinases (Cdk1 and -2) related to the inhibition of cell cycle progression. On the ...
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Sepúlveda Boza, Silvia; Delhvi, Sualaheen; Cassels Niven, Bruce (Pergamon Press Ltd., 1992-08-21)The rare dihydroquercetin 3-0-/3-0-xyloside, caryatin 7-0-/3-0-glucoside and the previously unknown 6-methoxylated flavonoid glycoside jaceidin 5-0-/3-0-glucoside were isolated from twigs of Eucryphia glutinosa where they ...
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Fierro, Angélica; Osorio Olivares, Mauricio; Cassels Niven, Bruce; Edmondson, Dale E.; Sepúlveda Boza, Silvia; Reyes Parada, Miguel (Elsevier Ltd., 2007-05-22)Abstract—Four enantiomerically pure (S)-4-alkylthioamphetamine derivatives were evaluated as monoamine oxidase (MAO) inhibitors using the human and rat isoforms of the enzyme. Molecular dockings were performed in order ...
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Osorio Olivares, Mauricio; Caroli Rezende, Marcos; Sepúlveda Boza, Silvia; Cassels Niven, Bruce; Fierro, Angélica (Elsevier Ltd., 2004-05-26)Abstract—Twenty-nine arylisopropylamines, substituted at the b-position of their side chain by an oxo, hydroxy, or methoxy group, were evaluated in vitro as MAO-A and MAO-B inhibitors. The oxo derivatives (‘cathinones’) ...
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Osorio Olivares, Mauricio; Rezende, Marcos Caroli; Sepúlveda Boza, Silvia; Cassels Niven, Bruce; Fierro, Angélica (2004)Twenty-nine arylisopropylamines, substituted at the β-position of their side chain by an oxo, hydroxy, or methoxy group, were evaluated in vitro as MAO-A and MAO-B inhibitors. The oxo derivatives ('cathinones') were in ...
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Hurtado Guzmán, Claudio; Fierro, Angélica; Iturriaga-Vásquez, Patricio; Sepúlveda Boza, Silvia; Cassels Niven, Bruce; Reyes Parada, Miguel (Taylor & Francis Ltd, 2003-03-10)(6)-4-Methylthioamphetamine (MTA) was resolved into its enantiomers, and a series of N-alkyl derivatives of the parent compound, as well as its a-ethyl analogue, were prepared. The monoamine oxidase (MAO) inhibitory properties ...
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Sepúlveda Boza, Silvia; Cassels Niven, Bruce (Thieme, 1996)Parasitic diseases are widespread in less developed countries, and are a major cause of suffering and inability of the affected populations to improve their own living conditions. Among these diseases, American trypanosomiasis ...
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Sepúlveda Boza, Silvia; Cassels Niven, Bruce (Thieme Medical Publishers, Inc., 1995-11-25)Parasitic diseases are widespread in less developed countries, and are a major cause of suffering and inability of the affected populations to improve their own living conditions. Among these diseases, American trypanosomiasis ...
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Cassels Niven, Bruce; Sepúlveda Boza, Silvia (Laboratorios Mixim S.A., 1988)Se describe la síntesis de una serie de 2-aril-l,3-dinitropropanos por condensación de benzaldehidos con nitrometano. Estos compuestos tienen utilidad potencial como precursores de 2-aril-1,3-dinitropropanos, los que ...
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Mejías, Lorenzo; Sepúlveda Boza, Silvia; Araya Maturana, Ramiro; Cassels Niven, Bruce; Caroli Rezende, Marcos (Marcel Dekker, Inc., 1998)Methods for the regioselective bromination of the title naphthalenone are described, wich lead to isomeric hydroquinones 5 or 6..