Browsing by Subject "ALZHEIMERS-DISEASE"

Now showing items 1-4 of 4

    • ApoE alleles and tau markers in patients with different levels of cognitive impairment 
      Lavados Montes, Manuel; Farías, Gustavo; Rothhammer Engel, Francisco; Guillón Moretti, Marta; Mujica, María; Maccioni, Cristóbal; Maccioni Baraona, Ricardo (ELSEVIER SCIENCE INC, 2005-09)
      Background. The presence of brain hyperphosphorylated tau constitutes a hallmark of neurodegenerative disorders of the Alzheimer's type. This report describes the relationships between tau markers in the cerebrospinal fluid ...
    • Gold Nanoparticles and Microwave Irradiation Inhibit Beta-Amyloid Amyloidogenesis 
      Araya, Eyleen; Olmedo, Ivonne; Bastus, Neus G.; Guerrero, Simón; Puntes, Víctor F.; Giralt, Ernest; Kogan Bocian, Marcelo (SPRINGER, 2008-11)
      Peptide-Gold nanoparticles selectively attached to beta-amyloid protein (A beta) amyloidogenic aggregates were irradiated with microwave. This treatment produces dramatic effects on the A beta aggregates, inhibiting both ...
    • Nanoparticle-mediated local and remote manipulation of protein aggregation 
      Kogan Bocian, Marcelo; Bastus, Neus G.; Amigo, Roger; Grillo-Bosch, Dolors; Araya, Eyleen; Turiel, Antonio; Labarta, Amilcar; Giralt, Ernest; Puntes, Víctor F. (AMER CHEMICAL SOC, 2006-01)
      The local heat delivered by metallic nanoparticles selectively attached to their target can be used as a molecular surgery to safely remove toxic and clogging aggregates. We apply this principle to protein aggregates, in ...
    • Regulation of Memory Formation by the Transcription Factor XBP1 
      Martínez, Gabriela; Vidal, Rene; Mardones, Pablo; Serrano, Felipe; Ardiles, Alvaro; Wirth, Craig; Valdés, Pamela; Thielen, Peter; Schneider, Bernard; Kerr, Bredford; Valdés Guerrero, José; Palacios, Adrián; Inestrosa, Nibaldo; Glimcher, Laurie; Hetz Flores, Claudio (CELL PRESS, 2016)
      Contextual memory formation relies on the induction of new genes in the hippocampus. A polymorphism in the promoter of the transcription factor XBP1 was identified as a risk factor for Alzheimer's disease and bipolar ...