Browsing by Subject "Alzheimer´s disease"

Now showing items 1-5 of 5

    • Gold Nanoparticles Mediate Improved Detection of beta-amyloid Aggregates by Fluorescence 
      Jara Guajardo, Pedro; Cabrera, Pablo; Celis, Freddy; Soler Jauma, Mónica; Berlanga Mora, Isadora; Parra Muñoz, Nicole; Acosta, Gerardo; Albericio, Fernando; Guzmán, Fanny; Campos, Marcelo; Álvarez, Alejandra; Morales Zavala, Francisco; Kogan, Marcelo J. (MDPI, 2020)
      The early detection of the amyloid beta peptide aggregates involved in Alzheimer's disease is crucial to test new potential treatments. In this research, we improved the detection of amyloid beta peptide aggregates in vitro ...
    • Mitochondrial permeability transition pore contributes to mitochondrial dysfunction in fibroblasts of ... 
      Pérez, María José; Ponce, Daniela P.; Aranguiz, Alejandra; Behrens Pellegrino, María Isabel; Quintanilla, Rodrigo A. (Elsevier B.V., 2018)
      © 2018 The Authors In the last few decades, many reports have suggested that mitochondrial function impairment is a hallmark of Alzheimer's disease (AD). Although AD is a neurodegenerative disorder, mitochondrial damage ...
    • Periodontitis and alzheimer's disease 
      Sansores España, Daniel; Carrillo Ávila, Arelly; Melgar Rodríguez, Samanta Azucena; Díaz Zúñiga, Jaime; Martínez Aguilar, Víctor (Medicina Oral, España, 2021)
      Background: Alzheimer's disease (AD), the main cause of dementia in the adult population, is characterized by a progressive loss of cognitive function. It is considered that neuroinflammation plays a fundamental role in ...
    • Redox modifications in synaptic components as biomarkers of cognitive status, in brain aging and disease 
      Muñoz, Pablo; Ardiles, Álvaro O.; Pérez Espinosa, Boris; Núñez Espinosa, Cristian; Paula Lima, Andrea; González Billault, Christian; Espinosa Parrilla, Yolanda (Elsevier, 2020)
      Aging is a natural process that includes several changes that gradually make organisms degenerate and die. Harman's theory proposes that aging is a consequence of the progressive accumulation of oxidative modifications ...
    • Serotype b of Aggregatibacter actinomycetemcomitans triggers pro-inflammatory responses and amyloid beta ... 
      Díaz Zúñiga, J.; Muñoz, Y.; Melgar Rodríguez, Samanta; More, J.; Bruna, B.; Lobos, P.; Monasterio, G.; Vernal Astudillo, Rolando; Paula Lima, A. (Taylor and Francis Ltd., 2019)
      Introduction: Previous reports have proposed that Periodontal disease (PDis) predisposes to Alzheimer’s disease (AD), both highly prevalent pathologies among the elderly. The bacteria Aggregatibacter actinomycetemcomitans ...