Browsing by Subject "Alzheimers disease"

Now showing items 1-2 of 2

    • Fine structure study of A beta(1-42) fibrillogenesis with atomic force microscopy 
      Arimon, M.; Diez Pérez, I.; Kogan Bocian, Marcelo; Durany, N.; Giralt, Ernest; Sanz, F.; Fernández Busquets, X. (FEDERATION AMER SOC EXP BIOL., 2005-05)
      One of the hallmarks of Alzheimer's disease is the self-aggregation of the amyloid beta peptide (A beta) in extracellular amyloid fibrils. Among the different forms of A beta, the 42-residue fragment (A beta(1-42)) readily ...
    • Improving the brain delivery of gold nanoparticles by conjugation with an amphipathic peptide 
      Guerrero, Simon; Araya, Eyleen; Fiedler Temer, Jenny; Arias, J.; Adura, Carolina; Albericio, Fernando; Giralt, Ernest; Arias, José; Fernández, María Soledad; Kogan Bocian, Marcelo (2010)
      Background & aims: Gold nanoparticles (GNPs) have promising applications for drug delivery as well as for the diagnosis and treatment of several pathologies, such as those related to the CNS. However, GNPs are retained in ...