Browsing by Subject "Anti-cancer agents"

Now showing items 1-2 of 2

    • Determinants of anti-cancer effect of mitochondrial electron transport chain inhibitors: Bioenergetic profile ... 
      Urra, Felix; Weiss López, Boris; Araya Maturana, Ramiro (Bentham Science Publishers B.V., 2016)
      © 2016 Bentham Science Publishers. Recent evidence highlights that energy requirements of cancer cells vary greatly from normal cells and they exhibit different metabolic phenotypes with variable participation of both ...
    • Small structural changes on a hydroquinone scaffold determine the complex I inhibition or uncoupling of ... 
      Urra Faúndez, Félix; Córdova Delgado, Miguel; Lapier, Michel; Orellana Manzano, Andrea; Acevedo Arévalo, Luis; Pessoa Mahana, Hernán; González Vivanco, Jaime; Martínez Cifuentes, Maximiliano; Ramírez Rodríguez, Oney; Millas Vargas, Juan; Weiss López, Boris; Pavani, Mario; Ferreira Parker, Jorge; Araya Maturana, Ramiro (Academic Press Elsevier Science, 2016)
      Mitochondria participate in several distinctiveness of cancer cell, being a promising target for the design of anti-cancer compounds. Previously, we described that ortho-carbonyl hydroquinone scaffold 14 inhibits the complex ...