Browsing by Subject "CD28"

Now showing items 1-2 of 2

    • Premature senescence of T-cells favors bone loss during osteolytic diseases. A new concern in the osteoimmunology ... 
      González Ouna, Luis Gustavo; Sierra Cristancho, Alfredo José; Rojas Pérez, Carolina Isabel; Cafferata Chea, Emilio Alfredo; Melgar Rodríguez, Samanta Azucena; Cárdenas Gutiérrez, Angélica María; Vernal Astudillo, Rolando Marcelo (International Society on Aging and Disease, USA, 2021)
      Cellular senescence is a biological process triggered in response to time-accumulated DNA damage, which prioritizes cell survival over cell function. Particularly, senescent T lymphocytes can be generated prematurely during ...
    • Senescent CD4+CD28− T lymphocytes as a potential driver of Th17/Treg imbalance and alveolar bone resorption ... 
      González Oosuna, Luis Gustavo; Sierra Cristancho, Alfredo José; Cafferata Chea, Emilio Alfredo; Melgar Rodríguez, Samanta Azucena; Rojas Pérez, Carolina Isabel; Carvajal Pavez, Paola Lorena; Cortez, Cristian; Vernal Astudillo, Rolando Marcelo (MDPI, 2022)
      Senescent cells express a senescence-associated secretory phenotype (SASP) with a pro-inflammatory bias, which contributes to the chronicity of inflammation. During chronic inflammatory diseases, infiltrating CD4(+) T ...