Browsing by Subject "Clinical Biochemistry"
Now showing items 1-20 of 84
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(1975)A human placental protein previously described is studied in order to expand its biological characterization. Dose response curve of its action on uterine growth of prepuberal mice showed to be a significant logarithmic ...
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(2007)A great body of experimental evidence collected over many years indicates that calcium has a central role in a variety of neuronal functions. In particular, calcium participates in synaptic plasticity, a neuronal process ...
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(Maney Publishing, 1997)The influence of acetaminophen (APAP) treatment (400 mg/kg) on Kupffer cell function was studied in the isolated perfused liver by colloidal carbon infusion, concomitantly with parameters related to oxidative stress ...
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(Kluwer Academic Publishers, 1975)1. Glucokinase is one of four glucose phos-phorylating enzymes present in rat liver. Its distinctive features are a high Km for glucose (high-Km isozyme) and a rather narrow substrate specificity. In contrast, the other ...
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(Wiley-Liss Inc., 2014)Copper is an essential cofactor of complex IV of the electron transfer chain, and it is directly involved in the generation of mitochondrial membrane potential. Its deficiency induces the formation of ROS, large mitochondria ...
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(Martinus Nijhoff/Dr. W. Junk Publishers, 1981)An adenylate cyclase activity was identified and characterized in preparations from Xenopus laevis ovarian tissue and follicles. The enzyme is more active in the presence of Mn2+ than of Mg2+, and it is highly activated ...
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Adrenal function during childhood and puberty in daughters of women with polycystic ovary syndrome (Endocrine Society, 2009)Context: In some patients, PCOS may develop as a consequence of an exaggerated adrenarche during pubertal development. Objective: The aim of the study was to assess adrenal function during childhood and pubertal development ...
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(1985)Ketoconazole, an imidazole derivative known to inhibit cytochrome P450-dependent adrenal enzymes was given to a patient with a functioning adrenal rest tumor of the liver in preparation for surgery. The drug was administered ...
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(1991)Studies on Salmonella typhi and Salmonella typhimurium outer membrane proteins have shown that the relative position of OmpC porin in sodium dodecyl sulfate‐polyacrylamide gel electrophoresis undergoes an important shift ...
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(2011)Soluble amyloid β-peptide oligomers (AβOs), increasingly recognized as causative agents of Alzheimer's disease (AD), disrupt neuronal Ca2+ homeostasis and synaptic function. Here, we report that AβOs at sublethal concentrations ...
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(2010)Amyotrophic lateral sclerosis (ALS) is the most common adult-onset motoneuron degenerative disease characterized by the selective loss of motoneurons in the spinal ventral horn, most brainstem nuclei, and the cerebral ...
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(Wiley-Liss Inc., 2017)© 2016 Wiley Periodicals, Inc. Diabetic kidney disease (DKD) is the major cause of end stage renal disease. Sodium tungstate (NaW) exerts anti-diabetic and immunomodulatory activities in diabetic animal models. Here, we ...
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(1967)(6,7-3H) oestradiol-17β incorporation by the rat uterus has been studied using autoradiography. The cytoplasm and/or the cellular membrane of uterine eosinophilic cells seems to incorporate oestradiol in a much greater ...
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(Endocrine Society, 2007)Context: Anti-Müllerian hormone (AMH) levels are increased in polycystic ovarian syndrome (PCOS), but it is not known whether other forms of hyperandrogenism, such as PCOS observed in women with type 1 diabetes mellitus ...
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(2009)Calcium/calmodulin-dependent protein kinase IV (CaMKIV) plays a key role in the regulation of calcium-dependent gene expression. The expression of CaMKIV and the activation of CREB regulated genes are involved in memory ...
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Certain large forms of circulating immunoreactive human growth hormone are in fact immunoglobulins (1990)To explain frequent discordances between serum GH levels and clinical manifestation of acromegaly, we investigated the possibility that certain immunoglobulins G (IgGs) might be responsible for the displacement of [125I]human ...
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(Endocrine Society, 2007)Context: At present, women with type 1 diabetes (DM1) are being treated with supraphysiological doses of exogenous insulin with the aim of providing a strict metabolic control, thereby avoiding the long-term complications ...
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(1991)Angiotensin II acts on adrenal glomerulosa cells to induce the phospholipase C-mediated generation of inositol trisphosphate and sn-1,2-diacyglycerol as the major products of inositol phospholipid breakdown. This last ...