Browsing by Subject "Diabetic cardiomyopathy"

Now showing items 1-4 of 4

    • Defective insulin signaling and mitochondrial dynamics in diabetic cardiomyopathy 
      Westermeier, Francisco; Navarro Márquez, Mario F.; López Crisosto, Camila; Bravo Sagua, Roberto; Quiroga Lagos, Clara; Bustamante, Mario; Verdejo, Hugo E.; Zalaquett Sepúlveda, Ricardo; Ibacache, Mauricio; Parra Ortíz, María Valentina; Castro, Pablo F.; Rothermel, Beverly A.; Hill, Joseph A.; Lavandero González, Sergio (Elsevier, 2015)
      Diabetic cardiomyopathy (DCM) is a common consequence of longstanding type 2 diabetes mellitus (T2DM) and encompasses structural, morphological, functional, and metabolic abnormalities in the heart.Myocardial energy metabolism ...
    • Diabetic cardiomyopathy and metabolic remodeling of the heart 
      Battiprolu, Pavan K.; López Crisosto, Camila; Wang, Zhao V.; Nemchenko, Andriy; Lavandero González, Sergio; Hill, Joseph A. (2013)
      The incidence and prevalence of diabetes mellitus are both increasing rapidly in societies around the globe. The majority of patients with diabetes succumb ultimately to heart disease, much of which stems from atherosclerotic ...
    • Emerging role of mitophagy in cardiovascular physiology and pathology 
      Morales, Pablo E.; Arias Durán, Carla; Ávalos Guajardo, Yáreni; Aedo, Geraldine; Verdejo, Hugo E.; Parra Ortiz, Valentina; Lavandero González, Sergio (Elsevier, 2020)
      Healthy mitochondrial function is imperative for most tissues, but especially those with a high energy demand. Robust evidence linking mitochondrial dysfunction with cardiovascular disease has demonstrated that mitochondrial ...
    • Quercetin prevents diastolic dysfunction induced by a high-cholesterol diet: role of oxidative stress and ... 
      Castillo, Rodrigo L.; Herrera Videla, Emilio; González Candia, Alejandro; Reyes Farías, Marjorie; Jara, Nicole de la; Peña, Juan Pedro; Carrasco Pozo, Catalina (Hindawi Ltd, 2018)
      Alterations in cardiac energy metabolism play a key role in the pathogenesis of diabetic cardiomyopathy. Hypercholesterolemia associated with bioenergetic impairment and oxidative stress has not been well characterized in ...