Browsing by Subject "Germline variations"

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    • Heritable genomic diversity in breast cancer driver genes and associations with risk in a chilean population 
      Morales Pison, Sebastián Felipe; González Hormazábal, Patricio Andrés; Tapia Pineda, Julio César; Salas Burgos, Alexis Marcelo; Ampuero Llanos, Sandra Patricia; Gómez, Fernando; Waugh, Enrique; Reyes, José Miguel; Jara Sosa, Lilian Elena Jonasa (BMC, 2022)
      Background Driver mutations are the genetic components responsible for tumor initiation and progression. These variants, which may be inherited, influence cancer risk and therefore underlie many familial cancers. The present ...