Browsing by Subject "Oxidative phosphorylation"

Now showing items 1-9 of 9

    • Alterations of rat liver mitochondrial oxidative phosphorylation and calcium uptake by benzo[a]pyrene 
      Salazar, Inés; Pavani, Mario; Aranda, Waldo; Maya Arango, Juan; Morello Casté, Antonio; Ferreira, Jorge (2004)
      We report that oxidative phosphorylation and Ca2+ uptake processes are enhanced in liver mitochondria isolated from benzo[a]pyrene (B[a]P)-treated rats. The carcinogen did not affect either the respiratory control index ...
    • Determinants of anti-cancer effect of mitochondrial electron transport chain inhibitors: Bioenergetic profile ... 
      Urra, Felix; Weiss López, Boris; Araya Maturana, Ramiro (Bentham Science Publishers B.V., 2016)
      © 2016 Bentham Science Publishers. Recent evidence highlights that energy requirements of cancer cells vary greatly from normal cells and they exhibit different metabolic phenotypes with variable participation of both ...
    • Energy requirements of odor transduction in the chemosensory cilia of olfactory sensory neurons rely on ... 
      Villar, Pablo; Delgado Arriagada, Ricardo; Vergara Montecinos, Cecilia; Reyes, Juan G.; Bacigalupo Vicuña, Juan (Soc Neuroscience, 2017-06-07)
      The mechanisms that power the physiological events occurring in cilia, flagella, and microvilli are of fundamental importance for the functions of these important and ubicuous organelles. The olfactory epithelium is mostly ...
    • Energy sources that fuel metabolic processes in protruding finger-like organelles 
      Villar, Pablo S.; Vergara Montecinos, Cecilia; Bacigalupo, Juan (Wiley, 2020)
      Cells possess a variety of organelles with characteristic structure and subcellular localization intimately linked to their specific function. While most are intracellular and found in virtually all eukaryotic cells, there ...
    • Fibrinogen-clotting enzyme, pictobin, fromBothrops pictus snake venom. Structural and functional characterization 
      Vivas Ruiz, Dan E.; Sandoval, Gustavo A.; González Kozlova, Edgar; Zarria Romero, Jacquelyne; Lazo, Fanny; Rodríguez, Edith; Magalhães, Henrique; Chávez Olortegui, Carlos; Oliveira, Luciana S.; Alvarenga, Valeria G.; Urra Faúndez, Félix; Toledo, Jorge; Yarlequé, Armando; Eble, Johannes A.; Sánchez, Eladio F. (Elsevier, 2020)
      A thrombin-like enzyme, pictobin, was purified from Bothrops pictus snake venom. It is a 41-kDa monomeric glycoprotein as showed by mass spectrometry and contains approx. 45% carbohydrate by mass which could be removed ...
    • Membrane actions of male contraceptive gossypol tautomers 
      Reyes, Juan E.; Wyrick, Steven D.; Borriero, Laura; Benos, Dale J. (1986)
      The role of different gossypol tautomers in the interaction of this molecule with membranes has been investigated using the isolated hemiacetal moiety of gossypol and the pH dependency of the keto-enol tautomeric equilibrium. ...
    • New insights on the role of lipid metabolism in the metabolic reprogramming of macrophages 
      Batista González, Ana; Vidal Álvarez, Roberto; Criollo Céspedes, Alfredo; Carreño Márquez, Leandro (Frontiers Media, 2020)
      Macrophage activation is intimately linked to metabolic reprogramming. Inflammatory (M1) macrophages are able to sustain inflammatory responses and to kill pathogens, mostly by relying on aerobic glycolysis and fatty acid ...
    • Reduced oxidative phosphorylation and proton efflux suggest reduced capillary blood supply in skeletal ... 
      Cea Muñoz, Gabriel; Bendahan, David; Manners, David; Hilton-Jones, David; Lodi, Raffaele; Styles, Peter; Taylor, Doris J. (Oxford University Press, 2002)
      Quantitative MRI and phosphorus magnetic resonance spectroscopy (31P-MRS) were used to investigate skeletal muscle metabolism in vivo in patients with dermatomyositis (DM) and polymyositis (PM) in order to evaluate the ...
    • Small structural changes on a hydroquinone scaffold determine the complex I inhibition or uncoupling of ... 
      Urra Faúndez, Félix; Córdova Delgado, Miguel; Lapier, Michel; Orellana Manzano, Andrea; Acevedo Arévalo, Luis; Pessoa Mahana, Hernán; González Vivanco, Jaime; Martínez Cifuentes, Maximiliano; Ramírez Rodríguez, Oney; Millas Vargas, Juan; Weiss López, Boris; Pavani, Mario; Ferreira Parker, Jorge; Araya Maturana, Ramiro (Academic Press Elsevier Science, 2016)
      Mitochondria participate in several distinctiveness of cancer cell, being a promising target for the design of anti-cancer compounds. Previously, we described that ortho-carbonyl hydroquinone scaffold 14 inhibits the complex ...