Browsing by Subject "Zebrafish"

Now showing items 1-20 of 35

    • Acid-sensing ion channel immunoreactivities in the cephalic neuromasts of adult zebrafish 
      Abbate, F.; Madrigrano, M.; Scopitteri, T.; Levanti, M.; Cobo, J. M.; Germana, Antonino; Vega Velásquez, Juan Andrés; Laurà, Rosaria (Elsevier, 2016)
      The neuromasts are the morphofunctional unit of the lateral line system serving as mechanosensors for water flow and movement. The mechanisms underlying the detection of the mechanical stimuli in the vertebrate mechanosensory ...
    • Acid-sensing ion channels and transient-receptor potential ion channels in zebrafish taste buds 
      Levanti, M.; Randazzo, B.; Viña, E.; Montalbano, G.; García Suárez, O.; Germanà, A.; Vega, J. A.; Abbate, F. (Elsevier, 2016)
      Sensory information from the environment is required for life and survival, and it is detected by specialized cells which togethermakeup the sensory system. The fish sensory system includes specialized organs that are ...
    • Altered electrochemical properties of iron oxide nanoparticles by carbon enhance molecular biocompatibility ... 
      Verma, S. K.; Thirumurugan, A.; Panda, P. K.; Patel, P.; Nandi, A.; Jha, E.; Prabakaran, K.; Udayabhaskar, R.; Mangalaraja, R. V.; Mishra, Y. K.; Akbari Fakhrabadi, A.; Morel, M. J.; Suar, M.; Ahuja, R. (Elsevier, 2021)
      Recent advancement in nanotechnology seeks exploration of new techniques for improvement in the molecular, chemical, and biological properties of nanoparticles. In this study, carbon modification of octahedral-shaped ...
    • Apical contacts stemming from incomplete delamination guide progenitor cell allocation through a dragging mechanism 
      Pulgar, Eduardo; Schwayer, Cornelia; Guerrero, Néstor; López, Loreto; Márquez, Susana; Hartel, Steffen; Soto, Rodrigo; Heisenberg, Carl-Philipp; Concha Nordemann, Miguel Luis Angel (Elife Sciences Publications, 2021)
      The developmental strategies used by progenitor cells to allow a safe journey from their induction place towards the site of terminal differentiation are still poorly understood. Here, we uncovered a mechanism of progenitor ...
    • Behavioral effects of triadimefon in zebrafish are associated with alterations of the dopaminergic and ... 
      Paredes Zúñiga, Susana; Trost, Nils; Paz, Javiera F. de la; Alcayaga Urbina, Julio; Allende Connelly, Miguel (Elsevier, 2019)
      Triadimefon (TDF) is a triazole fungicide extensively used in agriculture that has been found as a pollutant in numerous water sources. In mammals, it inhibits monoamine uptake through binding to the dopamine transporter, ...
    • Cloning of hif-1α and hif-2α and mRNA expression pattern during development in zebrafish 
      Rojas, Diego A.; Pérez Munizaga, Daniela A.; Centanin, Lazaro; Antonelli, Marcelo; Wappner, Pablo; Allende Connelly, Miguel; Reyes, Ariel E. (2007)
      Hypoxia-inducible factors (HIFs) regulate gene expression in response to hypoxia and in vertebrates they are known to participate in several developmental processes, including angiogenesis, vasculogenesis, heart and central ...
    • Combinatorial Fgf and Bmp signalling patterns the gastrula ectoderm into prospective neural and epidermal domains 
      Kudoh, Tetsuhiro; Concha, Miguel L.; Houart, Corinne; Dawid, Igor B.; Wilson, Stephen W. (2004)
      Studies in fish and amphibia have shown that graded Bmp signalling activity regulates dorsal-to-ventral (DV) patterning of the gastrula embryo. In the ectoderm, it is thought that high levels of Bmp activity promote epidermal ...
    • Comparative analysis of salmon cell lines and zebrafish primary cell cultures infection with the fish ... 
      Ortiz Severín, Javiera Rocío; Tandberg, Julia I.; Winther Larsen, Hanne C.; Chávez Espinosa, Francisco; Cambiazo Ayala, Liliana Verónica (MDPI, 2021)
      Piscirickettsia salmonis is the etiologic agent of piscirickettsiosis, a disease that causes significant losses in the salmon farming industry. In order to unveil the pathogenic mechanisms of P. salmonis, appropriate ...
    • Comparison of gene expression patterns of key growth genes between different rate growths in zebrafish ... 
      Opazo Salas, Rafael; Valladares Boasi, Luis; Romero Ormazábal, Jaime (Universidad Católica de Valparaíso, 2017)
      Variable individual growth rate is a phenomenon observed in fish cohorts that influences the aquaculture performance and fish cohort ecological viability. Our aim was to compare gene expression patterns of key growth genes ...
    • Compensatory growth renders Tcf7l1a dispensable for eye formation despite its requirement in eye field ... 
      Young, Rodrigo M.; Hawkins, Thomas A.; Cavodeassi, Florencia; Stickney, Heather L.; Schwarz, Quenten; Lawrence, Lisa M.; Wierzbicki, Claudia; Cheng, Bowie; Luo, Jingyuan; Ambrosio, Elizabeth Mayela; Klosner, Allison; Sealy, Ian M.; Rowell, Jasmine; Trivedi, Chintan A.; Bianco, Isaac H.; Allende Connelly, Miguel; Busch-Nentwich, Elisabeth M.; Gestri, Gaia; Wilson, Stephen W. (Elife Sciences Publ., 2019)
      The vertebrate eye originates from the eye field, a domain of cells specified by a small number of transcription factors. In this study, we show that Tcf7l1a is one such transcription factor that acts cell-autonomously to ...
    • Current advances in comprehending dynamics of regenerating axons and axon-glia interactions after peripheral ... 
      González, David; Allende Connelly, Miguel (MDPI, 2021)
      Following an injury, axons of both the central nervous system (CNS) and peripheral nervous system (PNS) degenerate through a coordinated and genetically conserved mechanism known as Wallerian degeneration (WD). Unlike ...
    • CXCL12a/CXCR4b acts to retain neutrophils in caudal hematopoietic tissue and to antagonize recruitment to ... 
      Paredes Zúñiga, Susana; Morales, Rodrigo A.; Muñoz Sánchez, Salomé; Muñoz Montecinos, Carlos Humberto.; Parada, Margarita; Tapia, Karina; Rubilar, Carlos; Allende Connelly, Miguel; Peña, Oscar A. (Springer Verlag, 2017)
      © 2017, Springer-Verlag Berlin Heidelberg. Neutrophils are a major component of the innate immune response and the most abundant circulating cell type in humans and zebrafish. The CXCL12/CXCR4 ligand receptor pair plays a ...
    • Elongator subunit 3 (Elp3) Is required for Zebrafish trunk development 
      Rojas Benítez, Diego; Allende Connelly, Miguel L. (MDPI, 2020)
      Transfer RNAs (tRNAs) are the most post-transcriptionally modified RNA species. Some of these modifications, especially the ones located in the anti-codon loop, are required for decoding capabilities of tRNAs. Such is the ...
    • Evaluating the capacity of human gut microorganisms to colonize the zebrafish larvae (Danio rerio) 
      Valenzuela, María José; Caruffo, Mario; Herrera, Yoani; Medina, Daniel A.; Coronado, Maximo; Feijoo, Carmen G.; Muñoz, Salomé; Garrido, Daniel; Troncoso, Miriam; Figueroa, Guillermo; Toro Ibaceta, Magaly Alejandra; Reyes Jara, Angélica; Magne, Fabien; Navarrete, Paola (Frontiers Media, 2018-05-29)
      In this study we evaluated if zebrafish larvae can be colonized by human gut microorganisms. We tested two strategies: (1) through transplantation of a human fecal microbiota and (2) by successively transplanting aerotolerant ...
    • Generation of mouse-zebrafish hematopoietic tissue chimeric embryos for hematopoiesis and host-pathogen ... 
      Parada-Kusz, Margarita; Penaranda, Cristina; Hagedorn, Elliott J.; Clatworthy, Anne; Nair, Anil V.; Henninger, Jonathan E.; Ernst, Christoph; Li, Brian; Riquelme, Raquel; Jijon, Humberto; Villablanca, Eduardo J.; Zon, Leonard I.; Hung, Deborah; Allende Connelly, Miguel (Company of Biologists Ltd, 2018)
      © 2018. Published by The Company of Biologists Ltd. Xenografts of the hematopoietic system are extremely useful as disease models and for translational research. Zebrafish xenografts have been widely used to monitor blood ...
    • Inhibition of the 3-Hydroxy-3-Methyl-Glutaryl-CoA Reductase Induces Orofacial Defects in Zebrafish 
      Signore Ahumada, Iskra; Jerez, Carolina; Figueroa, Diego; Suazo Sanhueza, José Lorenzo; Marcelain Cubillos, Katherine; Cerda Arancibia, Óscar; Colombo Flores, Alicia (Wiley, 2016)
      Background: Orofacial clefts (OFCs) are common birth defects, which include a range of disorders with a complex etiology affecting formation of craniofacial structures. Some forms of syndromic OFCs are produced by defects ...
    • Insights into the organization of dorsal spinal cord pathways from an evolutionarily conserved raldh2 ... 
      Castillo, Hozana A.; Cravo, Roberta M.; Azambuja, Ana P.; Simões-Costa, Marcos S.; Sura-Trueba, Sylvia; Gonzalez, Jose; Slonimsky, Esfir; Almeida, Karla; Abreu, José G.; Afonso de Almeida, Marcio A.; Sobreira, Tiago P.; de Oliveira, Saulo H.Pires; de Oliveira, Paulo (Company of Biologists Ltd, 2010)
      Comparative studies of the tetrapod raldh2 (aldh1a2) gene, which encodes a retinoic acid (RA) synthesis enzyme, have led to the identification of a dorsal spinal cord enhancer. Enhancer activity is directed dorsally to the ...
    • Intestinal transcriptome analysis reveals enrichment of genes associated with immune and lipid mechanisms, ... 
      Valenzuela, Luis; Pacheco, Sebastián; Rincón, Gonzalo; Pavez, Leonardo; Lam, Natalia; Hernández, Adrián J.; Dantagnan, Patricio; González, Felipe; Jilberto Vallejos, Felipe Ignacio; Ravanal, M. Cristina; Ramos, Cecilia; García, Héctor; Araneda Tolosa, Cristian; Ulloa, Pilar E. (MDPI, 2021)
      The molecular mechanisms underlying fish tolerance to soybean meal (SBM) remain unclear. Identifying these mechanisms would be beneficial, as this trait favors growth. Two fish replicates from 19 experimental families ...
    • Lef1-dependent Wnt/β-catenin signalling drives the proliferative engine that maintains tissue homeostasis ... 
      Valdivia, Leonardo E.; Young, Rodrigo M.; Hawkins, Thomas A.; Stickney, Heather L.; Cavodeassi, Florencia; Schwarz, Quenten; Pullin, Lisa M.; Villegas, Rosario; Moro, Enrico; Argenton, Francesco; Allende Connelly, Miguel; Wilson, Stephen W. (2011)
      During tissue morphogenesis and differentiation, cells must self-renew while contemporaneously generating daughters that contribute to the growing tissue. How tissues achieve this precise balance between proliferation and ...
    • Live-cell imaging of Salmonella Typhimurium interaction with zebrafish larvae after injection and immersion ... 
      Varas, Macarena; Fariña, Alonso; Díaz Pascual, Francisco; Ortíz-Severín, Javiera; Marcoleta, Andrés E.; Allende Connelly, Miguel; Santiviago, Carlos A.; Chávez, Francisco P. (Elsevier B.V., 2017)
      © 2017The zebrafish model has been used to determine the role of vertebrate innate immunity during bacterial infections. Here, we compare the in vivo immune response induced by GFP-tagged Salmonella Typhimurium inoculated ...