Browsing by Subject "miRNAs"

Now showing items 1-8 of 8

    • A Role for mir-26a in Stress: A Potential sEV Biomarker and Modulator of Excitatory Neurotransmission 
      Lafourcade, Carlos Andrés; Fernández, Anllely; Ramírez, Juan Pablo; Corvalán, Katherine; Carrasco, Miguel Ángel; Iturriaga, Andrés; Bátiz, Luis Federico; Luarte, Alejandro; Wyneken, Úrsula (MDPI, 2020)
      Stress is a widespread problem in today's societies, having important consequences on brain function. Among the plethora of mechanisms involved in the stress response at the molecular level, the role of microRNAs (miRNAs) ...
    • Association between single-nucleotide polymorphisms in miRNA and breast cancer risk: an updated review 
      Arancibia, Trinidad; Morales Pisón, Sebastián; Maldonado Maldonado, Edio Luis; Jara Sosa, Lilian Elena (Sociedad de Biología de Chile, 2021)
      Breast cancer (BC), a heterogeneous, aggressive illness with high mortality, is essentially a genomic disease. While the high-penetrance genes BRCA1 and BRCA2 play important roles in tumorigenesis, moderate- and ...
    • Deletion of hippocampal glucocorticoid receptors unveils sex-biased microRNA expression and neuronal ... 
      Tejos Bravo, Macarena Verónica Monserrat; Oakley, Robert H.; Whirledge, Shannon D.; Corrales Ibáñez, Wladimir Antonio; Silva, Juan Pablo; García Rojo, Gonzalo Javier; Toledo, Jorge; Sánchez, Wendy; Román Albasini, Luciano Paolo; Aliaga, Esteban; Aguayo Abarca, Felipe Ignacio; Olave Olave, Felipe Antonio; Maracaja Coutinho, Vinicius; Cidlowski b, John A.; Fiedler Temer, Jenny Lucy (Elsevier, 2021)
      Sex differences in the brain have prompted many researchers to investigate the underlying molecular actors, such as the glucocorticoid receptor (GR). This nuclear receptor controls gene expression, including microRNAs ...
    • Exploring the expression of pro-inflammatory and hypoxia-related microRNA-20a, MicroRNA-30e, and microRNA-93 ... 
      Chaparro, Alejandra; Lozano, Mauricio; Gaedechens, Dominique; López, Carolina; Albers, Daniela; Hernández Ríos, Emma Marcela; Pascual, Andrés; Nart, José; Irarrazabal, Carlos E. (MDPI, 2022)
      Hypoxia associated with inflammation are common hallmarks observed in several diseases, and it plays a major role in the expression of non-coding RNAs, including microRNAs (miRNAs). In addition, the miRNA target genes for ...
    • MicroRNAs miR-21a and miR-93 are down regulated in peripheral blood mononuclear cells (PBMCs) from patients ... 
      Salas Pérez, Francisca; Codner Dujovne, Ethel; Valencia, Elizabeth; Pizarro, Carolina; Carrasco, Elena; Pérez Bravo, Francisco (Elsevier, 2013)
      Introduction: It is well established that type 1 diabetes (T1D) is an autoimmune disease. Controversial data exists regarding the differential control of the immune system in T1D patients compared to unaffected individuals. ...
    • miR15a and miR16 in Chilean type 1 diabetes patients: possible association with apoptosis, inflammatory, ... 
      García Díaz, Diego; Camacho-Guillén, P.; Codner Dujovne, Ethel; Pérez Bravo, Francisco (Springer International Publishing, 2018)
      © 2018, Italian Society of Endocrinology (SIE). Aim: Type 1 diabetes mellitus (T1D) is an autoimmune disease characterized by the progressive destruction of β cells, mediated by the interaction between T cells and several ...
    • miR15a and miR16 in Chilean type 1 diabetes patients: possible association with apoptosis, inflammatory, ... 
      García Díaz, Diego; Camacho-Guillén, Patricia; Codner Dujovne, Ethel; Pérez Bravo, Francisco (Springer International Publishing, 2018)
      © 2018 Italian Society of Endocrinology (SIE) Aim: Type 1 diabetes mellitus (T1D) is an autoimmune disease characterized by the progressive destruction of β cells, mediated by the interaction between T cells and several ...
    • New Molecular Insights of Insulin in Diabetic Cardiomyopathy 
      Westermeier, Francisco; Riquelme, Jaime A.; Pavez, Mario; Garrido, Valeria; Díaz, Ariel; Verdejo, Hugo E.; Castro, Pablo F.; García Nannig, Lorena; Lavandero González, Sergio (Frontiers Media S.A., 2016-04)
      Type 2 diabetes mellitus (T2DM) is a highly prevalent disease worldwide. Cardiovascular disorders generated as a consequence of T2DM are a major cause of death related to this disease. Diabetic cardiomyopathy (DCM) is ...