Browsing by Author "981177d1-7602-449c-9fc7-577136c4fc39"

Now showing items 1-2 of 2

    • Nonsyndromic orofacial clefts in Chile: LINE-1 methylation and MTHFR variants 
      Cáceres Rojas, Gabriela; Salamanca, Carlos; Krause, Bernardo J.; Recabarren, Andrea S.; Recabarren, Pamela; Pantoja Parada, Pedro; Leiva Villagra, Noemi; Pardo Vargas, Rosa; Santos, José Luis; Suazo Sanhueza, José Lorenzo (Future Medicine, 2020)
      Aim: To evaluate the risk of nonsyndromic orofacial clefts (NSOFCs) associated with LINE-1 methylation, as a marker of global DNA methylation, and the effect of MTHFR functional variants on this variable. Patients & methods: ...
    • Untitled 
      Salamanca, Carlos; González Hormazábal, Patricio; Recabarren, Andrea S.; Recabarren, Pamela A.; Pantoja, Roberto; Leiva Villagra, Noemí; Pardo Vargas, Rosa; Suazo Sanhueza, José Lorenzo (2020)
      Background TheS-adenosyl-methionine (SAM) availability is crucial for DNA methylation, an epigenetic mechanism involved in nonsyndromic cleft lip with or without cleft palate (NSCL/P) expression. The aim of this study was ...