Now showing items 1-6 of 6

    • Cafferatta Chea, Emilio; Castro Saavedra, Sebastián; Fuentes Barros, Gonzalo; Melgar Rodríguez, Samanta; Rivera Rodríguez, Felipe; Carvajal Pavez, Paola; Hernández Ríos, Emma; Cortés, Bastián; Cortez, Cristian; Cassels Niven, Bruce; Vernal Astudillo, Rolando (Wiley, 2020)
      Background During periodontitis, tooth-supporting alveolar bone is resorbed when there is an increased expression of the pro-osteolytic factor termed receptor activator of nuclear factor kappa B ligand (RANKL), which is ...
    • Alvarez Rivas, Carla; Benítez Cravero, Alvaro; Rojas, Leticia; Pujol, Myriam; Carvajal Pavez, Paola; Díaz Zúñiga, Jaime; Vernal Astudillo, Rolando (Univ Sao Paulo Fac Odontologia Bauru, 2015)
      In Aggregatibacter actinomycetemcomitans, different serotypes have been described based on LPS antigenicity. Recently, our research group has reported a differential immunogenicity when T lymphocytes were stimulated with ...
    • Díaz Zúñiga, Jaime; Melgar Rodríguez, Samanta; Monasterio, Gustavo; Pujol, Myriam; Rojas, Leticia; Alvarez, Carla; Carvajal, Paola; Vernal Astudillo, Rolando (Elsevier Ltd, 2017)
      Objective: In Aggregatibacter actinomycetemcomitans, different serotypes have been described based on lipopolysaccharide (LPS) antigenicity. When T lymphocytes were stimulated with these serotypes, different patterns of ...
    • Monasterio, Gustavo; Ormeño Castillo, Francisca; Astorga, Jéssica; Hoare Teuche, Anilei; Terraza, Claudia; Cafferata, Emilio A.; Villablanca, Eduardo J.; Vernal Astudillo, Rolando Marcelo (Frontiers Media, 2020)
      Aggregatibacter actinomycetemcomitans is a Gram-negative oral bacterium with high immunostimulatory and pathogenic potential involved in the onset and progression of periodontitis, a chronic disease characterized by aberrant ...
    • González Ouna, Luis Gustavo; Sierra Cristancho, Alfredo José; Rojas Pérez, Carolina Isabel; Cafferata Chea, Emilio Alfredo; Melgar Rodríguez, Samanta Azucena; Cárdenas Gutiérrez, Angélica María; Vernal Astudillo, Rolando Marcelo (International Society on Aging and Disease, USA, 2021)
      Cellular senescence is a biological process triggered in response to time-accumulated DNA damage, which prioritizes cell survival over cell function. Particularly, senescent T lymphocytes can be generated prematurely during ...
    • González Oosuna, Luis Gustavo; Sierra Cristancho, Alfredo José; Cafferata Chea, Emilio Alfredo; Melgar Rodríguez, Samanta Azucena; Rojas Pérez, Carolina Isabel; Carvajal Pavez, Paola Lorena; Cortez, Cristian; Vernal Astudillo, Rolando Marcelo (MDPI, 2022)
      Senescent cells express a senescence-associated secretory phenotype (SASP) with a pro-inflammatory bias, which contributes to the chronicity of inflammation. During chronic inflammatory diseases, infiltrating CD4(+) T ...