Now showing items 1-2 of 2

    • Neogenin1 is a Sonic Hedgehog target in medulloblastoma and is necessary for cell cycle progression 

      Milla Brito, Luis Apolo; Arros Villanueva, Andrea Marisol; Espinoza, Natalie; Remke, Marc; Kool, Marcel; Taylor, Michael D.; Pfister, Stefan M.; Wainwright, Brandon J.; Palma Alvarado, Verónica (UICC, 2014)
      The canonical Sonic Hedgehog (Shh)/Gli pathway plays multiples roles during central nervous system (CNS) development. To elucidate the molecular repertoire of Shh mediators, we have recently described novel transcriptional ...
    • Proliferation of Murine Midbrain Neural Stem Cells Depends upon an Endogenous Sonic Hedgehog (Shh) Source 

      Martínez, Constanza; Cornejo, Víctor Hugo; Lois, Pablo; Ellis, Tammy; Solis, Natalia P.; Wainwright, Brandon J.; Palma Alvarado, Verónica (PLoS ONE, 2013)
      The Sonic Hedgehog (Shh) pathway is responsible for critical patterning events early in development and for regulating the delicate balance between proliferation and differentiation in the developing and adult vertebrate ...