Browsing by Author "Ivorra, M. Dolores"

Now showing items 1-4 of 4

    • N-SUBSTITUTION AND a,-ADRENERGIC RECEPTOR AFFlNITV OJi'LAUDANOSINE ANALOGUES 
      Iturriaga-Vásquez, Patricio; Cassels Niven, Bruce; Ivorra, M. Dolores; D’Ocon, M. Pilar (Sociedad Chilena de Química, 2006)
      Benzyltetrahydroisoquinoline (BTHIQ) molecules are able to adopt widely differing conformations that depend on the presence or absence of N-substituents. To assess the possible role of BTHIQ conformation on the affinity ...
    • N-substitution and alpha(1)-adrenergic receptor affinity of laudanosine analogues 
      Iturriaga-Vásquez, Patricio; Cassels Niven, Bruce; Ivorra, M. Dolores; Dxocon, M. Pilar (SOCIEDAD CHILENA DE QUIMICA, 2006-09)
      Benzyltetrahydroisoquinoline (BTHIQ) molecules are able to adopt widely differing conformations that depend on the presence or absence of N-substituents. To assess the possible role of BTHIQ conformation on the affinity ...
    • N-SUBSTITUTION AND α1-ADRENERGIC RECEPTOR AFFINITY OF LAUDANOSINE ANALOGUES 
      Iturriaga-Vásquez, Patricio; Cassels Niven, Bruce; Ivorra, M. Dolores; D’Ocon, M. Pilar (Sociedad Chilena de Química, 2006-09)
      Benzyltetrahydroisoquinoline (BTHIQ) molecules are able to adopt widely differing conformations that depend on the presence or absence of N-substituents. To assess the possible role of BTHIQ conformation on the affinity ...
    • Simplified Tetrandrine Congeners as Possible Antihypertensive Agents with a Dual Mechanism of Action 
      Iturriaga-Vásquez, Patricio; Miquel, Raquel; Ivorra, M. Dolores; D’Ocon, M. Pilar; Cassels Niven, Bruce (American Chemical Society and American Society of Pharmacognosy, 2003-02-07)
      A series of O- and/or N-substituted derivatives of (()-coclaurine (1a) were synthesized as simplified structural mimics of the antihypertensive alkaloid tetrandrine (2) and assayed for binding to brain cortical sites ...