Browsing by Author "Loyola, Luis Alberto"

Now showing items 1-6 of 6

    • Activity of semi-synthetic mulinanes against MDR, pre-XDR, and XDR strains of mycobacterium tuberculosis 
      Martínez González, María Alejandrina; Peña Rodríguez, Luis Manuel; Uc-Cachón, Andrés Humberto; Bórquez, Jorge; Simirgiotis, Mario J.; Barrios García, Hugo Brígido; Hernández Pando, Rogelio; Loyola, Luis Alberto; Areche Medina, Carlos Alberto; Dzul-Beh, Ángel de Jesús; Barrios Payan, Jorge Alberto; Mata Espinosa, Dulce; Escalante Erosa, Fabiola; García Sosa, Karlina; Molina Salinas, Gloria María (MDPI, 2021)
      Tuberculosis causes more than 1.2 million deaths each year. Worldwide, it is the first cause of death by a single infectious agent. The emergence of drug-resistant strains has limited pharmacological treatment of the ...
    • Antituberculosis activity of natural and semisynthetic azorellane and mulinane diterpenoids 
      Molina Salinas, Gloria María; Bórquez, Jorge; Ardiles, Alejandro; Said Fernández, Salvador; Loyola, Luis Alberto; San Martín Barrientos, Aurelio; González Collado, Isidro; Peña Rodríguez, Luis Manuel (ELSEVIER, 2010)
      The antituberculosis activity of 14 natural azorellane and mulinane diterpenoids isolated from Azorella compacta, Azorella madreporica, Mulinum crassifolium, and Laretia acaulis, together with eight semisynthetic ...
    • Bioactive metabolites from the Andean flora. Antituberculosis activity of natural and semisynthetic azorellane ... 
      Molina Salinas, Gloria María; Bórquez, Jorge; Ardiles, Alejandro; Said Fernández, Salvador; Loyola, Luis Alberto; Yam Puc, Alejandro; Becerril Montes, Pola; Escalante Erosa, Fabiola; San Martín Barrientos, Aurelio; González Collado, Isidro; Peña Rodríguez, Luis Manuel (SPRINGER, 2010-02-17)
      Natural products are recognized as an important source of new and better pharmaceuticals for the treatment of diseases such as tuberculosis. The azorellane and mulinane diterpenoids represent an interesting group of ...
    • Diterpenoids from Azorella madreporica and their Antibacterial Activity 
      Areche Medina, Carlos; Vaca Cerezo, Inmaculada; Loyola, Luis Alberto; Bórquez, Jorge; Rovirosa, Juana; San Martín Barrientos, Aurelio (GEORG THIEME VERLAG KG, 2010-10)
      Two new diterpenoids, mulin-12-en-16-al-20-oic acid and 13-alpha-hydroxy-mulin-11-en-14-one-20-oic acid, were isolated from Azorella madreporica. Their structures were identified on the basis of one-dimensional and ...
    • Microbial transformation of the diterpene mulin-11,13-dien-20-oic acid by Mucor plumbeus 
      Areche Medina, Carlos; Loyola, Luis Alberto; Bórquez, Jorge; Rovirosa, Juana; San Martín Barrientos, Aurelio (JOHN WILEY, 2008-08)
      Two new mulinane-type derivatives: 16-hydroxy mulin-11,13-dien-20-oic (2) acid and 7 alpha,16-dihydroxy mulin-11,13-dien-20-oic (3) acid were obtained by microbial transformation of mulin-11,13-dien-20-oic acid (1), along ...
    • Yaretol, a norditerpenoid from Azorella madreporica 
      Loyola, Luis Alberto; Bórquez, Jorge; Morales, Glauco; San Martín Barrientos, Aurelio; Manríquez Castro, Víctor; Boys Mardones, Daphne; Darias, José (American Chemical Society, 2002-11)
      A new norditerpenoid, yaretol (1), was isolated from the whole plant of Azorella madreporica. The structure of 1 was established by one- and two-dimensional NMR techniques and confirmed by X-ray diffraction analysis.