Browsing by Author "Speisky Cosoy, Hernán"

Now showing items 1-5 of 5

    • Anti-inflarnrnatory and antipyretic effects of boldine 
      Backhouse Erazo, Nadine; Delporte Vergara, Carla; Givernau, M.; Cassels Niven, Bruce; Valenzuela, A.; Speisky Cosoy, Hernán (Birkhäuser Verlag, 1994-03-02)
      Boldine, an antioxidant alkaloid isolated from Peumus boldus, exhibits a dose-dependent anti-inflammatory activity in the carrageenan-induced guinea pig paw edema test with an oral EDso of 34 mg/kg. Boldine also reduces ...
    • ANTIOXIDANT PROPERTIES OF THE ALKALOID BOLDINE IN SYSTEMS UNDERGOING LIPID PEROXIDATION AND ENZYME INACTlVATION 
      Speisky Cosoy, Hernán; Cassels Niven, Bruce; Lissi Gervaso, Eduardo A.; Videla Cabrera, Luis (Pergamon Press, 1990-11-30)
      Boldine, in low micromolar concentrations, was able to prevent brain bomogenate autooxidatíon, the 2,2'·uobis(2·amidinopropane)(AAP)·induced Iipid peroxidation of red cell plasma rnembranes, and the AAP·induced inactivation ...
    • E ffects of some antioxidative aporphine derivatives on striatal dopaminergic transmission and on MPTP-induced ... 
      Loghin, Felicia; Chagraoui, Abdeslam; Asencio, Marcelo; Comoy, Etienne; Speisky Cosoy, Hernán; Cassels Niven, Bruce; Protais, Philippe (Elsevier Science B.V., 2002-11-20)
      (S)-(1)-boldine, an aporphine alkaloid displaying antioxidative and dopaminergic properties, and six of its derivatives (glaucine, 3-bromoboldine, 3-iodoboldine, 8-aminoboldine, 8-nitrosoboldine and 2,9-O,O9 -dipivaloylboldine) ...
    • Efecto de un extracto seco de boldo sobre el tránsito intestinal oro-cecal en voluntarios sanos 
      Gotteland, Martín; Espinoza Madariaga, Julio; Cassels Niven, Bruce; Speisky Cosoy, Hernán (Sociedad Médica de Santiago, 1995-06-27)
      Boldo (Peumus boldus Molina) is a widely used medicinal planto However, its pbysiological effects are not well known. Recent studies in animals sbmoed tbat certain components o/ boldo relax smootb muscle and prolong ...
    • Protective Effect of Boldine in Experimental Colitis 
      Gotteland, Martín; Jiménez, Inés; Brunser, Oscar; Guzmán, Leda; Romero, Sergio; Cassels Niven, Bruce; Speisky Cosoy, Hernán (Georg Thieme, 1996-11-23)
      The cytoprotective and anti-inflammatory effects of boldine in an experimental model of acute colitis are reported. The administration of boldine to animals with colitis induced by the intrarectal administration of ...