Browsing by Author "Stefani, Enrico"

Now showing items 1-3 of 3

    • A conducting state with properties of a slow inactivated state in a Shaker K+ channel mutant 
      Olcese, Riccardo; Sigg, Daniel; Latorre, Ramón; Bezanilla, Francisco; Stefani, Enrico (ROCKEFELLER UNIV PRESS, 2001-02)
      In Shaker K+ channel, the amino terminus deletion Delta6-46 removes fast inactivation (N-type) unmasking a slow inactivation process. In Shaker Delta6-46 (Sh-IR) background, two additional mutations (T449V-I470C) remove ...
    • Correlation between charge movement and ionic current during slow inactivation in Shaker K+ channels 
      Olcese, Riccardo; Latorre, Ramón; Toro, Ligia; Bezanilla, Francisco; Stefani, Enrico (ROCKEFELLER UNIV PRESS, 1997-11)
      Prolonged depolarization induces a slow inactivation process in some Ki channels. We have studied ionic and gating currents during long depolarizations in the mutant Shaker H4-Delta(6-46) K+ channel and in the nonconducting ...
    • Voltage-controlled gating in a large conductance Ca2+-sensitive K(+)channel (hslo) 
      Stefani, Enrico; Ottolia, M.; Noceti, F.; Olcese, Riccardo; Wallner, Martín; Latorre, Ramón; Toro, Ligia (NATL ACAD SCIENCES, 1997-05-13)
      Large conductance calcium- and voltage-sensitive K+ (MaxiK) channels share properties of voltage- and ligand-gated ion channels. In voltage-gated channels, membrane depolarization promotes the displacement of charged ...