Browsing by Subject "NADPH oxidase"

Now showing items 1-4 of 4

    • A feed-forward mechanism involving the NOX complex and RyR-mediated Ca2 release during axonal specification 
      Wilson, Carlos; Muñoz Palma, Ernesto; Henríquez, Daniel R.; Palmisano, Ilaria; Núñez González, Marco; Di Giovanni, Simone; González Billault, Christian (Soc Neuroscience, 2016)
      Physiological levels of ROS support neurite outgrowth and axonal specification, but the mechanisms by which ROS are able to shape neurons remain unknown. Ca2+, a broad intracellular second messenger, promotes both Rac1 ...
    • Actin Filaments—A Target for Redox Regulation 
      Wilson, Carlos; Terman, Jonathan R.; Ahmed, Giasuddin (Wiley, 2016)
      Actin and its ability to polymerize into dynamic filaments is critical for the form and function of cells throughout the body. While multiple proteins have been characterized as affecting actin dynamics through noncovalent ...
    • Dissecting the role of redox signaling in neuronal development 
      Bórquez Muñoz, Daniel; Urrutia, Pamela J.; Wilson, Carlos; Van Zundert, Brigitte; Núñez González, Marco; González Billault, Christian (Wiley-Blackwell, 2016)
      The generation of abnormally high levels of reactive oxygen species (ROS) is linked to cellular dysfunction, including neuronal toxicity and neurodegeneration. However, physiological ROS production modulates redox-sensitive ...
    • From birth to death: a role for reactive oxygen species in neuronal development 
      Wilson, Carlos; Muñoz Palma, Ernesto; González Billault, Christian (Elsevier, 2018-08)
      Historically, ROS have been considered toxic molecules, especially when their intracellular concentration reaches high values. However, physiological levels of ROS support crucial cellular processes, acting as second ...