Browsing by Author "05c6f6a7-9c54-49d8-9e25-13df68b95d0b"

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    • Metabolic stress - Induced activation of FoxO1 triggers diabetic cardiomyopathy in mice 
      Battiprolu, Pavan K.; Hojayev, Berdymammet; Jiang, Nan; Wang, Zhao V.; Luo, Xiang; Iglewski, Myriam; Shelton, John M.; Gerard, Robert D.; Rothermel, Beverly A.; Gillette, Thomas G.; Lavandero González, Sergio; Hill, Joseph A. (2012)
      The leading cause of death in diabetic patients is cardiovascular disease; diabetic cardiomyopathy is typified by alterations in cardiac morphology and function, independent of hypertension or coronary disease. However, ...
    • Mitochondrial fission and autophagy in the normal and diseased heart 
      Iglewski, Myriam; Hill, Joseph A.; Lavandero González, Sergio; Rothermel, Beverly A. (2010)
      Sustained hypertension promotes structural, functional and metabolic remodeling of cardiomyocyte mitochondria. As long-lived, postmitotic cells, cardiomyocytes turn over mitochondria continuously to compensate for changes ...