Now showing items 1-3 of 3

    • Defective insulin signaling and mitochondrial dynamics in diabetic cardiomyopathy 

      Westermeier, Francisco; Navarro Márquez, Mario F.; López Crisosto, Camila; Bravo Sagua, Roberto; Quiroga Lagos, Clara; Bustamante, Mario; Verdejo, Hugo E.; Zalaquett, Ricardo; Ibacache, Mauricio; Parra Ortíz, María Valentina; Castro, Pablo F.; Rothermel, Beverly A.; Hill, Joseph A.; Lavandero González, Sergio (Elsevier, 2015)
      Diabetic cardiomyopathy (DCM) is a common consequence of longstanding type 2 diabetes mellitus (T2DM) and encompasses structural, morphological, functional, and metabolic abnormalities in the heart.Myocardial energy metabolism ...
    • Dexmedetomidine protects the heart against ischemia-reperfusion injury by an endothelial eNOS/NO dependent mechanism 

      Riquelme, Jaime; Westermeier, Francisco; Hall, Andrew R.; Vicencio, Jose; Pedrozo Cibils, Zully; Ibacache, Mauricio; Fuenzalida, Barbara; Sobrevia, Luis; Davidson, Sean M.; Yellon, Derek M.; Sanchez, Gina; Lavandero González, Sergio (Elsevier, 2016)
      The alpha2-adrenergic receptor agonist Dexmedetomidine (Dex) is a sedative medication used by anesthesiologists. Dex protects the heart against ischemia-reperfusion (IR) and can also act as a preconditioning mimetic. The ...
    • Influence of glucose metabolism on vascular smooth muscle cell proliferation 

      Chiong Lay, Mario; Morales, Pablo Esteban; Torres, Gloria; Gutiérrez, Tómas; García Nannig, Lorena; Ibacache, Mauricio; Michea Acevedo, Luis (Hans Huber, 2013)
      Diff erentiation of vascular smooth muscle cells (VSMC) is an essential process of vascular development. VSMC have biosynthetic, proliferative, and contractile roles in the vessel wall. Alterations in the diff erentiated ...