Now showing items 1-14 of 14

    • Active metabolites and biological activities from Malesherbia auristipulata 

      Erazo, Silvia; Negrete Córdova, Rosa; Zaldívar San Román, María Mercedes; Backhouse Erazo, Nadine; Belmonte, E.; Rojas, Oriana; San Martín, Aníbal; Masson Salaué, Lilia; García, R.; Delporte Vergara, Carla (University of Salerno, 2006)
      The antimicrobial activity of the resinous exudate from the aerial part of Malesherbia auristipulata showed an active mixture against Gram (+) bacteria: S.aureus, B. subtilis and M. flavus and less active against Gram (-) ...
    • Active metabolites from Dunalia spinosa resinous exudates 

      Erazo, Silvia; Rocco Troquian, Giovanna Edith; Zaldívar San Román, María Mercedes; Delporte Vergara, Carla; Backhouse Erazo, Nadine; Castro, Consuelo; Belmonte, E.; Delle Monache, F.; García, R. (VERLAG Z NATURFORSCH, 2008-07)
      Dunalia sphiosa, a plant used in folk medicine for toothaches, breathing problems and cleansing wounds. was found active as antimicrobial and antioxidant. A new (E)-aurone rutinoside (dunaurone) has been isolated from the ...
    • Antibacterial diterpenoids from Fabiana densa var. ramulosa 

      Erazo, Silvia; Zaldívar San Román, María Mercedes; Delporte Vergara, Carla; Backhouse Erazo, Nadine; Tapia, P.; Belmonte, E.; Delle Monache, F.; Negrete Córdova, Rosa (GEORG THIEME VERLAG KG, 2002-04)
      A biologically monitored fractionation of the resinous exudate of Fabiana densa Remy var. ramulosa Wedd. led to the isolation of the two new diterpenes: ent-beyer-15-en-18-O-succinate and ent-beyer-15-en-18-O-oxalate as ...
    • Antimicrobial activity of Psoralea glandulosa L. 

      Erazo, Silvia; González, V.; Zaldívar San Román, María Mercedes; Negrete Córdova, Rosa (SWETS ZEITLINGER PUBLISHERS, 1997-12)
      Antimicrobial activity of leaf extracts of Psoralea glandulosa L. (Papilionaceae) is reported This study was carried out on the extracts and on the plant's most abundant metabolite, bakuchiol. Antimicrobial activity against ...
    • Constituents and biological activities of Schinus polygamus 

      Erazo, Silvia; Delporte Vergara, Carla; Negrete Córdova, Rosa; García, Rubén; Zaldívar San Román, María Mercedes; Iturra, Gladys; Caballero, Esther; López, José Luis; Backhouse Erazo, Nadine (ELSEVIER, 2006-10-11)
      The folk medicine employs Schinus polygamus to treat arthritic pain and cleansing of wounds. As no reports of pharmacological studies supporting its anti-inflammatory and analgesic properties, extracts of increasing polarity ...
    • Growth-phase regulation of lipopolysaccharide O-antigen chain length influences serum resistance in serovars of Salmonella 

      Bravo Rodríguez, Denisse; Silva Valenzuela, Cecilia Alejandra; Carter Jaña, Javier Antonio; Hoare Teuche, Anilei Paz; Álvarez Armijo, Sergio Aníbal; Blondel, Carlos; Zaldívar San Román, María Mercedes; Valvano, Miguel A.; Contreras, Inés (SOC GENERAL MICROBIOLOGYJournal Of Medical Microbiology, vol. 57 Issue 8 p. 938-946 AUG 2008, 2008-08)
      The amount of lipopolysaccharide (LPS) O antigen (OAg) and its chain length distribution are important factors that protect bacteria from serum complement. Salmonella enterica serovar Typhi produces LPS with long chain ...
    • Infection of Mice by Salmonella enterica Serovar Enteritidis Involves Additional Genes That Are Absent in the Genome of Serovar Typhimurium 

      Silva, Cecilia A.; Blondel, Carlos J.; Quezada, Carolina P.; Porwollik, Steffen; Andrews Polymenis, Helene L.; Toro, Cecilia S.; Zaldívar San Román, María Mercedes; Contreras, Inés; McClelland, Michael; Santiviago Cid, Carlos (AMER SOC MICROBIOLOGY, 2012-02)
      Salmonella enterica serovar Enteritidis causes a systemic, typhoid-like infection in newly hatched poultry and mice. In the present study, a library of 54,000 transposon mutants of S. Enteritidis phage type 4 (PT4) strain ...
    • Longitudinal analysis of metalloproteinases, tissue inhibitors of metalloproteinases and clinical parameters in gingival crevicular fluid from periodontitis-affects patients 

      Pozo, P.; Valenzuela, María Antonieta; Melej, C.; Zaldívar San Román, María Mercedes; Puente Piccardo, Javier; Martínez, B.; Gamonal Aravena, Jorge Antonio (BLACKWELL MUNKSGAARD, 2005-06)
      Background: The aim of this work was to improve the assessment of the periodontal disease status through measurements of extracellular matrix metalloprote nases (MMPs) and their tissular inhibitors (TIMPs) in the gingival ...
    • Methyl psilalate: A new antimicrobial metabolite from Psila boliviensis 

      Erazo, Silvia; Negrete Córdova, Rosa; Zaldívar San Román, María Mercedes; Backhouse Erazo, Nadine; Delporte Vergara, Carla; Silva, I.; Belmonte, E.; López Pérez, J. L.; San Feliciano, Arturo (GEORG THIEME VERLAG KG, 2002-01)
      Psila boliviensis (Wedd.) Cabr. yielded a new phenylpropanoid, named methyl psilalate. The structure was established by means of standard spectroscopic techniques. The microbiological evaluation of the compound revealed ...
    • O-antigen expression in Salmonella enterica serovar Typhi is regulated by nitrogen availability through RpoN-mediated transcriptional control of the rfaH gene 

      Bittner, Mauricio; Saldías, Soledad; Estévez, C.; Zaldívar San Román, María Mercedes; Marolda, Cristina; Valvano, Miguel A.; Contreras, Inés (SOC GENERAL MICROBIOLOGY, 2002-12)
      The authors previously reported increased expression of the Salmonella enterica serovar Typhi (S. typhi) rfaH gene when the bacterial cells reach stationary phase. In this study, using a lacZ fusion to the rfaH promoter ...
    • O-antigen modal chain length in Shigella flexneri 2a is growth-regulated through RfaH-mediated transcriptional control of the wzy gene 

      Carter Jaña, Javier Antonio; Blondel, Carlos; Zaldívar San Román, María Mercedes; Álvarez Armijo, Sergio Aníbal; Marolda, Cristina L.; Valvano, Miguel A.; Contreras, Inés (SOC GENERAL MICROBIOLOGY, 2007-10)
      Shigella flexneri 2a 2457T produces lipopolysaccharide (LIPS) with two O-antigen (OAg) chain lengths: a short (S-OAg) controlled by WzzB and a very long (VL-OAg) determined by Wzz(pHS-2). This study demonstrates that the ...
    • The outer core lipopolysaccharide of Salmonella enterica Serovar typhi is required for bacterial entry into epithelial cells 

      Hoare, Anilei; Bittner, Mauricio; Carter, Javier; Álvarez Armijo, Sergio Aníbal; Zaldívar San Román, María Mercedes; Bravo, Denisse; Valvano, Miguel A.; Contreras, Inés (AMER SOC MICROBIOLOGY, 2006-03)
      Salmonella enterica serovar Typhi causes typhoid fever in humans. Central to the pathogenicity of serovar Typhi is its capacity to invade intestinal epithelial cells. The role of lipopolysaccharide (LPS) in the invasion ...
    • Spontaneous Excision of the Salmonella enterica Serovar Enteritidis-Specific Defective Prophage-Like Element SE14 

      Santiviago Cid, Carlos; Blondel, Carlos; Quezada, Carolina P.; Silva, Cecilia A.; Tobar, Pia M.; Porwollik, Steffen; McClelland, Michael; Andrews Polymenis, Helene L.; Toro, Cecilia S.; Zaldívar San Román, María Mercedes; Contreras, Inés (2010-04)
      Salmonella enterica serovar Enteritidis has emerged as a major health problem worldwide in the last few decades. DNA loci unique to S. Enteritidis can provide markers for detection of this pathogen and may reveal pathogenic ...
    • The rfaH gene, which affects lipopolysaccharide synthesis in Salmonella enterica serovar Typhi, is differentially expressed during the bacterial growth phase 

      Rojas, Gonzalo; Saldías, Soledad; Bittner, Mauricio; Zaldívar San Román, María Mercedes; Contreras, Inés (Elsevier Sciences B. V., 2001)
      We have cloned and sequenced the rfaH gene from Salmonella enterica serovar Typhi Strain Ty2. The gene shoed a high degree of similirity to the rfaH genes from Escherichia coli K-12 and S. enterica serovar Typhimurium. A ...