Now showing items 1-2 of 2

    • The IKK complex contributes to the induction of autophagy 

      Criollo Céspedes, Alfredo; Senovilla, Laura; Authier, Helene; Maiuri, M. C.; Morselli, E.; Vitale, I.; Kepp, O.; Tasdemir, E.; Galluzzi, Lorenzo; Shen, S.; Tailler, M.; Delahaye, N.; Tesniere, A.; De Stefano, D.; Ben Younes, Amena; Harper, F.; Pierron, G.; Lavandero González, Sergio; Zitvogel, L.; Israel, A; Baud, V; Kroemer, Guido (NATURE PUBLISHING GROUP, 2010-02-03)
      In response to stress, cells start transcriptional and transcription-independent programs that can lead to adaptation or death. Here, we show that multiple inducers of autophagy, including nutrient depletion, trigger the ...
    • The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1 

      Vicencio, José Miguel; Ortíz, C.; Criollo Céspedes, Alfredo; Jones, A. W. E.; Kepp, O.; Galluzzi, Lorenzo; Joza, N.; Vitale, I.; Morselli, E.; Tailler, M.; Castedo, M.; Maiuri, M. C.; Molgó, Jordi; Szabadkai, G.; Lavandero González, Sergio; Kroemer, Guido (NATURE PUBLISHING GROUP, 2009-07)
      The inositol 1,4,5-trisphosphate receptor (IP3R) is a major regulator of apoptotic signaling. Through interactions with members of the Bcl-2 family of proteins, it drives calcium (Ca2+) transients from the endoplasmic ...