Browsing by Author "82400122-42fa-4077-b23c-a51214dd0baa"

Now showing items 1-4 of 4

    • A convenient synthesis of benzo[g]pyrrolo[3,2-c]quinoline-6,11-diones 
      Tapia, Ricardo; López, Claudio; Morello Casté, Antonio; Maya Arango, Juan; Valderrama, Jaime (2005)
      The synthesis of a new class of angular tetracyclic quinones is described. Our strategy involves Diels-Alder reaction of pyrroloquinolinequinone 9, generated in situ from pyrroloquinoline 8, and dienes. The required ...
    • Access to quinazolines from 2-nitrobenzaldehyde and arylamines 
      Valderrama, Jaime A.; Pessoa Mahana, Hernán; Sarras, Gabriela; Tapia, Ricardo (1999)
      A synthesis of N-(2-nitrobenzyl)acetanilide (5) and (11) from 2- nitrobenzaldehyde and aromatic amines is reported. The reaction of amides (5) and (11) with iron in acetic acid-ethanol-water provided the corresponding 3- ...
    • Modulatory Effect of 2-(4-Hydroxyphenyl)amino-1,4-naphthoquinone on Endothelial Vasodilation in Rat Aorta 
      Palacios, Javier; Cifuentes, Fredi; Valderrama, Jaime A.; Benites, Julio; Ríos, David; González, Constanza; Chiong Lay, Mario; Cartes Saavedra, Benjamín; Lafourcade, Carlos; Wyneken, Úrsula (2016)
      The vascular endotheliumplays an essential role in the control of the blood flow. Pharmacological agents like quinone (menadione) at various doses modulate this process in a variety of ways. In this study, Q7, a ...
    • Synthesis of indazol-4,7-dione derivatives as potential trypanocidal agents 
      Tapia, Ricardo A.; Carrasco, Claudia; Ojeda, Scarlet; Salas, Cristian; Valderrama, Jaime A.; Morello Casté, Antonio; Repetto Scaramelli, Yolanda (2002)
      The synthesis of new indazol-4,7-dione derivatives via 1,3-dipolar cycloaddition of diazomethane with 2,3-dimethyl-1,4-benzoquinone (2) and 1,4-naphthoquinone (7) followed by N-alkylation of the pyrazol nitrogen atom of ...