Now showing items 1-14 of 14

    • Silva Valenzuela, Cecilia; Molina Quiroz, Roberto; Desai, Prerak; Valenzuela, Camila; Porwollik, Steffen; Zhao, Ming; Hoffman, Robert M.; Andrews-Polymenis, Helene; Contreras, Inés; Santiviago Cid, Carlos; McClelland, Michael (Frontiers Media, 2016)
      Two pools of individual single gene deletion (SOD) mutants of S. Typhimurium 14028s encompassing deletions of 3,923 annotated non-essential ORFs and sRNAs were screened by intraperitoneal (IP) injection in BALB/c mice ...
    • Blondel Buijuy, Carlos; Jiménez Muñoz, Juan; Leiva Araya, Lorenzo; Alvarez Armijo, Sergio; Pinto Anwandter, Bernardo; Contreras Leiva, Francisca; Pezoa Aros, David; Santiviago Cid, Carlos; Contreras Osorio, Lucia (American Society for Microbiology, 2015)
      In Fig. 2B, the RNA polymerase sigma 70 Western blots from the supernatant fractions of strains harboring an Hcp1-3XFLAG fusion were inadvertently duplicated during assembly of the final figure, and the blots of the sigma ...
    • Porwollik, Steffen; Santiviago Cid, Carlos; Cheng, Pui; Long, Fred; Desai, Prerak; Fredlund, Jennifer; Srikumar, Shabarinath; Silva, Cecilia A.; Chu, Weiping; Chen, Xin; Canals, Rocío; Reynolds, M. Megan; Bogomolnaya, Lydia; Shields, Christine; Cui, Ping; Guo, Jinbai; Zheng, Yi; Endicott Yazdani, Tiana; Yang, Hee-Jeong; Maple, Aimee; Ragoza, Yury; Blondel, Carlos J.; Valenzuela, Camila; Andrews Polymenis, Helene; McClelland, Michael (PLOS One, 2014)
      We constructed two collections of targeted single gene deletion (SGD) mutants and two collections of targeted multi-gene deletion (MGD) mutants in Salmonella enterica sv Typhimurium 14028s. The SGD mutant collections ...
    • Molina Quiroz, Roberto C.; Silva, Cecilia A.; Molina, Cristian F.; Leiva, Lorenzo E.; Reyes Cerpa, Sebastián; Contreras, Inés; Santiviago Cid, Carlos (Royal Soc., 2015)
      It has been proposed that sub-inhibitory concentrations of antibiotics play a role in virulence modulation. In this study, we evaluated the ability of Salmonella enterica serovar Typhimurium (hereafter S. Typhimurium) to ...
    • Fernández, Paulina; Velásquez, Felipe; Garcias-Papayani, Héctor; Amaya, Fernando; Ortega, Jaime; Gómez, Sebastian; Santiviago Cid, Carlos; Álvarez, Sergio A. (Frontiers Media SA., 2018-06)
      Lipid A is the bioactive component of lipopolysaccharide, and presents a dynamic structure that undergoes modifications in response to environmental signals. Many of these structural modifications influence Salmonella ...
    • Bello, J.; Sáez, D.; Escalona, E.; Velozo, P.; Santiviago Cid, Carlos; Contreras, I.; Oñate, A. (Cambridge Univ. Press., 2016)
      Salmonella Enteritidis is the main cause of foodborne salmonellosis worldwide. The limited effectiveness of current interventions against this pathogen has been the main incentive to develop new methods for the efficient ...
    • Silva Valenzuela, Cecilia; Velásquez, Felipe; Peñailillo, Johany; Garcías Papayani, H éctor; Fernández, Paulina; Tobar, Pía; Contreras, Inés; Santiviago Cid, Carlos; Álvarez Armijo, Sergio (Elsevier, 2016)
      Lipopolysaccharide (LPS) consists of three covalently linked domains: the lipid A, the core region and the O antigen (OAg), consisting of repeats of an oligosaccharide. Salmonella enterica serovar Enteritidis (S. Enteritidis) ...
    • Pezoa, David; Blondel Buijuy, Carlos José; Silva Valenzuela, Cecilia Alejandra; Yang, Hee-Jeong; Andrews Polymenis, Helene; Santiviago Cid, Carlos; Contreras, Inés (BioMed Central, 2014)
      The type VI secretion system (T6SS) is a virulence factor for many Gram-negative bacteria. Salmonella genus harbors five phylogenetically distinct T6SS loci encoded in Salmonella Pathogenicity Islands (SPIs) SPI-6, SPI-19, ...
    • Riquelme, Sebastián; Varas, Macarena; Valenzuela, Camila; Velozo Hermosilla, Paula Elizabeth; Chahin, Nicolás; Aguilera, Paulina; Sabag, Andrea; Labra, Bayron; Álvarez Armijo, Sergio; Chávez, Francisco P.; Santiviago Cid, Carlos (Frontiers Media, 2016)
      The social amoeba Dictyostelium discoideum has proven to be a useful model for studying relevant aspects of the host-pathogen interaction. In this work, D. discoideum was used as a model to study the ability of Salmonella ...
    • Silva Valenzuela, Cecilia A.; Desai, Prerak; Molina Quiroz, Roberto C.; Pezoa, David; Zhang, Yong; Porwollik, Steffen; Zhao, Ming; Hoffman, Robert M.; Contreras, Inés; Santiviago Cid, Carlos; McClelland, Michael (Impact Journals, 2016)
      Therapeutic attenuated strains of Salmonella Typhimurium target and eradicate tumors in mouse models. However, the mechanism of S. Typhimurium for tumor targeting is still poorly understood. We performed a high-throughput ...
    • Valenzuela, Camila; Gil, Magdalena; Urrutia, Ítalo M.; Sabag, Andrea; Enninga, Jost; Santiviago Cid, Carlos (Wiley, 2021)
      The ability ofSalmonellato survive and replicate within mammalian host cells involves the generation of a membranous compartment known as theSalmonella-containing vacuole (SCV).Salmonellaemploys a number of effector proteins ...
    • Velásquez, Juan C.; Hidalgo, Alejandro A.; Villagra, Nicolás; Santiviago Cid, Carlos; Mora, Guido C.; Fuentes, Juan A. (Microbiology Soc, 2016)
      The genomic island 9 (SPI-9) from Salmonella enterica serovar Typhi (S. Typhi) carries three ORFs (STY2876, STY2877, STY2878) presenting 98% identity with a type 1 secretory apparatus (T1SS), and a single ORF (STY2875) ...
    • Blondel, Carlos J.; Jiménez, Juan C.; Leiva, Lorenzo E.; Álvarez Armijo, Sergio Aníbal; Pinto, Bernardo I.; Contreras, Francisca; Pezoa, David; Santiviago Cid, Carlos; Contreras, Inés (American Society for Microbiology, 2013-04)
      Salmonella enterica serotype Gallinarum is the causative agent of fowl typhoid, a disease characterized by high morbidity and mortality that causes major economic losses in poultry production. We have reported that S. ...
    • Pezoa, David; Yang, Hee Jeong; Blondel, Carlos J.; Santiviago Cid, Carlos; Andrews Polymenis, Helene L.; Contreras, Inés (PLOS ONE, 2013)
      The role of the Salmonella Pathogenicity Islands (SPIs) in pathogenesis of Salmonella enterica Typhimurium infection in the chicken is poorly studied, while many studies have been completed in murine models. The Type VI ...