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    • Increased expression of mature cathepsin B in aging rat liver 

      Keppler, Daniel; Walter, Robin; Pérez, Claudio; Sierra, Felipe (Springer Verlag, 2000)
      Senescence has been proposed as an important safeguard against neoplasia. One of the hallmarks of cellular senescence in vitro as well as human aging in vivo is a reduced intracellular protein catabolism. The pathways ...