Now showing items 1-2 of 2

    • Cortisol/cortisone ratio and matrix metalloproteinase-9 activity are associated with pediatric primary hypertension 

      Martínez Aguayo, Alejandro; Campino, Carmen; Baudrand, René; Carvajal, Cristian; Garcia, Hernán; Aglony, Marlene; Bancalari, Rodrigo; García Nannig, Lorena; Loureiro, Carolina; Vecchiola, Andrea; Tapia Castillo, Alejandra; Valdivia, Carolina; Sanhueza, Sebastián; Fuentes, Cristóbal; Lagos, Carlos F.; Solari, Sandra; Allende, Fidel; Kalergis, Alexis; Fardella, Carlos E. (Lippincott Williams & Wilkins, 2016)
      Objective: To identify novel biomarkers associated with pediatric primary hypertension. Methods: We recruited 350 participants (4-16 years). Anthropometric parameters and aldosterone, plasma renin activity, cortisol, ...
    • Polymorphisms in the RAC1 gene are associated with hypertension risk factors in a chilean pediatric population 

      Tapia Castillo, Alejandra; Carvajal, Cristian A.; Campino, Carmen; Vecchiola, Andrea; Allende, Fidel; Solari, Sandra; García Nannig, Lorena; Lavandero González, Sergio; Valdivia, Carolina; Fuentes, Cristobal; Lagos, Carlos F.; Martínez Aguayo, Alejandro; Baudrand, René; Aglony, Marlene; García, Hernán; Fardella, Carlos E. (Oxford University Press, 2014)
      The GTPase Rac1 has been implicated in hypertension as a modulator of mineralocorticoid receptor activity. Our aim is to investigate the frequency of polymorphisms rs10951982 (intron 1, G>A) and rs836478 (intron 3, T>C) ...