Browsing by Author "XX568981"

Now showing items 21-40 of 66

    • Erratum: Ion Pair Method to Determine the Ctab Content in Gold Nanorods Samples (Journal of the Chilean ... 
      Adura, Carolina; Guzman, Fanny; Álvarez Lueje, Alejandro; Kogan Bocian, Marcelo (Sociedad Chilena de Quimica, 2015)
    • Exploring the influence of diels–alder linker length on photothermal molecule release from gold nanorods 
      Vetterlein, Claudia; Vásquez Salfate, Rodrigo; Bolaños, Karen; Acosta, Gerardo A.; Guzman, Fanny; Albericio, Fernando; Celis, Freddy; Campos, Marcelo; Kogan Bocian, Marcelo; Araya, Eyleen (Elsevier, 2018-06)
      We studied the photothermal release of carboxyfluorescein (CF) linked to the gold surface of gold nanorods (GNRs) by two Diels-Alder adducts of different lengths (n = 4 and n = 9). The functionalized GNRs were irradiated ...
    • Fine structure study of A beta(1-42) fibrillogenesis with atomic force microscopy 
      Arimon, M.; Diez Pérez, I.; Kogan Bocian, Marcelo; Durany, N.; Giralt, Ernest; Sanz, F.; Fernández Busquets, X. (FEDERATION AMER SOC EXP BIOL., 2005-05)
      One of the hallmarks of Alzheimer's disease is the self-aggregation of the amyloid beta peptide (A beta) in extracellular amyloid fibrils. Among the different forms of A beta, the 42-residue fragment (A beta(1-42)) readily ...
    • Flow chemistry to control the synthesis of nano and microparticles for biomedical applications 
      Hassan, Natalia; Oyarzún Ampuero, Felipe; Muñoz Lara, Pablo; Guerrero, Simón; Cabuil, Valérie; Abou-Hassan, Ali; Kogan Bocian, Marcelo (Bentham Science Publishers B.V., 2014)
      In this article we review the flow chemistry methodologies for the controlled synthesis of different kind of nano and microparticles for biomedical applications. Injection mechanism has emerged as new alternative for the ...
    • Gastric cancer: Nanoparticles as tools to improve treatment efficacy 
      Guerrero, Ariel R.; Oyarzún Ampuero, Felipe; Hassan, Natalia; Corvalán, Alejandro; Quest, Andrew F. G.; Kogan Bocian, Marcelo (Bentham Science, 2016)
      In recent years, advances in nanotechnology have raised the specter of developing effective agents for the treatment of high-impact diseases, like gastric cancer, which remains one of the major causes of cancer deaths ...
    • Gold nanoparticle based double‑labeling of melanoma extracellular vesicles to determine the specificity of ... 
      Lara, Pablo; Palma Florez, Sujey; Salas Huenuleo, Edison; Polakovicova, Iva; Guerrero, Simón; Lobos González, Lorena; Campos, América; Muñoz, Luis; Jorquera Cordero, Carla; Varas Godoy, Manuel; Cancino, Jorge; Arias, Eloísa; Villegas, Jaime; Cruz, Luis J.; Albericio, Fernando; Araya, Eyleen; Corvalán, Alejandro H.; Quest, Andrew F. G.; Kogan Bocian, Marcelo (BMC, 2020)
      Background Extracellular vesicles (EVs) have shown great potential for targeted therapy, as they have a natural ability to pass through biological barriers and, depending on their origin, can preferentially accumulate at ...
    • Gold nanoparticle-membrane interactions: Implications in biomedicine 
      Riveros, Ana; Dadlani, Komal; Salas, Edison; Caballero, Leonardo; Melo, Francisco; Kogan Bocian, Marcelo (American Scientific Publishers, 2013)
      There has been an increase in the research towards the use of nanoparticles as a promising tool for nanomedicine, from imagenology, drug and gene delivery, to phototherapy. Little is known regarding the interaction between ...
    • Gold Nanoparticles and Microwave Irradiation Inhibit Beta-Amyloid Amyloidogenesis 
      Araya, Eyleen; Olmedo, Ivonne; Bastus, Neus G.; Guerrero, Simón; Puntes, Víctor F.; Giralt, Ernest; Kogan Bocian, Marcelo (SPRINGER, 2008-11)
      Peptide-Gold nanoparticles selectively attached to beta-amyloid protein (A beta) amyloidogenic aggregates were irradiated with microwave. This treatment produces dramatic effects on the A beta aggregates, inhibiting both ...
    • Gold nanoparticles as an efficient drug delivery system for GLP - 1 peptides 
      Pérez Ortiz, Magdalena; Zapata Urzua, Claudio; Acosta, Gerardo A.; Álvarez Lueje, Alejandro; Albericio, Fernando; Kogan Bocian, Marcelo (Elsevier, 2017)
      In this work, the potential application of gold nanoparticles for GLP-1 analogues delivery was studied. For this purpose, the original sequence of the incretin GLP-1 was slightly modified in the C-terminal region by adding ...
    • Gold nanoparticles for photothermally controlled drug release 
      Guerrero, Ariel R.; Hassan, Natalia; Escobar, Carlos A.; Albericio, Fernando; Kogan Bocian, Marcelo; Araya, Eyleen (Future Medicine Ltd., 2014)
      © 2014 Future Medicine Ltd. In this article, we describe how nanoparticles work in photothermally triggered drug delivery, starting with a description of the plasmon resonance and the photothermal effect, and how this is ...
    • Gold nanoparticles for selective and remote heating of β-amyloid protein aggregates 
      Bastus, Neus G.; Kogan Bocian, Marcelo; Amigo, Roger; Grillo-Bosch, Dolors; Araya, Eyleen; Turiel, Antonio; Labarta, Amilcar; Giralt, Ernest; Puntes, Victor F. (2007)
      Nanoparticles can be made to respond resonantly to a time-varying electromagnetic field with advantageous results related to the transfer of energy from the exciting field to the nanoparticles. The surface of each particle ...
    • Gold nanoparticles interacting with β-cyclodextrin-phenylethylamine inclusion complex: a ternary system for ... 
      Sierpe, Rodrigo; Lang, Erika; Jara, Paul; Guerrero, Ariel; Chornik, Boris; Kogan Bocian, Marcelo; Yutronic Sáez, Nicolás (American Chemical Society, 2015)
      We report the synthesis of a 1:1 beta-cydodextrin-phenylethylamine (beta CD-PhEA) inclusion complex (IC) and the adhesion of gold nanoparticles (AuNPs) onto micro crystals of this complex, which forms a ternary system. The ...
    • Gold nanoparticles stabilized with beta cyclodextrin -2 - amino -4 -(4-chlorophenyl) thiazole complex: a ... 
      Asela, I.; Noyong, M.; Simon, U.; Andrades Lagos, Juan Andrés; Campanini Salinas, J.; Vásquez Velásquez, David; Kogan Bocian, Marcelo; Yutronic Sáez, Nicolás; Sierpe, R. (Public Library Science, 2017)
      While 2-amino-4-(4-chlorophenyl)thiazole (AT) drug and thiazole derivatives have several biological applications, these compounds present some drawbacks, such as low aqueous solubility and instability. A new complex of ...
    • Growth Kinetics of Gold Nanorods Synthesized by a Seed-Mediated Method Under pH Acidic Conditions 
      Almada, M.; Ruiz, E. D.; Ibarra Hurtado, J.; Hassan, N.; Kogan Bocian, Marcelo; Cadena Nava, R. D.; Valdés, M. A.; Juarez, J. (Amer Scientific, 2016)
      A systematic study of the effect of ascorbic acid concentration on the growth kinetics of gold nanorods under pH acidic conditions was done. We employed the seed-mediated approach at pH 1.25 using different ascorbic acid/Au+3 ...
    • How Changes in the Sequence of the Peptide CLPFFD-NH2 Can Modify the Conjugation and Stability of Gold ... 
      Olmedo, Ivonne; Araya, Eyleen; Sanz, Fausto; Medina, Elias; Arbiol, Jordi; Toledo, Pedro; Álvarez Lueje, Alejandro; Giralt, Ernest; Kogan Bocian, Marcelo (American Chemical Society, 2008-05-30)
      In a previous work, we studied the interaction of -amyloid fibrils (A ) with gold nanoparticles (AuNP) conjugated with the peptide CLPFFD-NH2. Here, we studied the effect of changing the residue sequence of the ...
    • How changes in the sequence of the peptide CLPFFD-NH2 can modify the conjugation and stability of gold ... 
      Olmedo Alegría, Ivonne Odette; Araya, Eyleen; Sanz, F.; Medina Consuegra, Elías Daniel; Arbiol, Jordi; Toledo, P.; Álvarez Lueje, Alejandro; Giralt, Ernest; Kogan Bocian, Marcelo (AMER CHEMICAL SOC, 2008-06)
      In a previous work, we studied the interaction of P-amyloid fibrils (A beta) with gold nanoparticles (AuNP) conjugated with the peptide CLPFFD-NH2. Here, we studied the effect of changing the residue sequence of the peptide ...
    • Improving cell penetration of gold nanorods by using an amphipathic arginine rich peptide 
      Riveros Salvatierra, Ana; Eggeling, Cynthia; Riquelme Barrios, Sebastián; Adura, Carolina; López Iglesias, Carmen; Guzmán, Fanny; Araya Fuentes, Eyleen; Almada, Mario; Juárez, Josue; Valdez, Miguel A.; Fuentevilla Morgado, Ignacio; López, Olga; Kogan Bocian, Marcelo (Dove Medical Press, 2020)
      Introduction: Gold nanorods are highly reactive, have a large surface-to-volume ratio, and can be functionalized with biomolecules. Gold nanorods can absorb infrared electromagnetic radiation, which is subsequently dispersed ...
    • Improving gold nanorod delivery to the central nervous system by conjugation to the shuttle Angiopep-2 
      Velasco Aguirre, Carolina; Morales Zavala, Francisco; Salas Huenuleo, Edison; Gallardo Toledo, Eduardo; Andonie, Oscar; Muñoz, Luis; Rojas, Ximena; Acosta, Gerardo; Sánchez Navarro, Macarena; Giralt, Ernest; Araya, Eyleen; Albericio, Fernando; Kogan Bocian, Marcelo (Future Medicine, 2017)
      Aim: To improve the in vivo delivery of gold nanorods (GNRs) to the central nervous system of rats, these gold nanoparticles were conjugated to Angiopep-2, a shuttle peptide that can cross the blood-brain barrier. Materials ...
    • Improving the brain delivery of gold nanoparticles by conjugation with an amphipathic peptide 
      Guerrero, Simon; Araya, Eyleen; Fiedler Temer, Jenny; Arias, J.; Adura, Carolina; Albericio, Fernando; Giralt, Ernest; Arias, José; Fernández, María Soledad; Kogan Bocian, Marcelo (2010)
      Background & aims: Gold nanoparticles (GNPs) have promising applications for drug delivery as well as for the diagnosis and treatment of several pathologies, such as those related to the CNS. However, GNPs are retained in ...
    • Inhibition of HIV-2(ROD) replication in a lymphoblastoid cell line by the alpha 1-antitrypsin Portland ... 
      Bahbouhi, B.; Bendjennat, M.; Chiva, C.; Kogan Bocian, Marcelo; Albericio, F.; Giralt, Ernest; Seidah, N. G.; Bahraoui, E. (EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2001-11)
      We investigated the effects of alpha1-antitrypsine Portland variant (alpha1-PDX) and decanoylRVKRchloromethylketone (decRVKRcmk) on HIV-2(ROD) replication in the Jurkat lymphoblastoid cell line. To this end, cells were ...