Browsing by Author "Adasme, Tatiana"

Now showing items 1-2 of 2

    • IGF-1 protects cardiac myocytes from hyperosmotic stress-induced apoptosis via CREB 
      Maldonado, Carola; Cea, Paola; Adasme, Tatiana; Collao, Andrés; Díaz Araya, Guillermo; Chiong Lay, Mario; Lavandero González, Sergio (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2005-11-04)
      Hyperosmotic stress stimulates a rapid and pronounced apoptosis in cardiac myocytes which is attenuated by insulin-like growth factor-1 (IGF-1). Because in these cells IGF-1 induces intracellular Ca2+ increase, we assessed ...
    • The transcription factor MEF2C mediates cardiomyocyte hypertrophy induced by IGF-1 signaling 
      Muñoz, Juan Pablo; Collao, Andrés; Chiong Lay, Mario; Maldonado Vera, Carola Patricia; Adasme, Tatiana; Carrasco Alarcón, Loreto del Pilar; Ocaranza Osses, Paula; Bravo Méndez, Roberto; González, Leticia; Díaz Araya, Guillermo; Hidalgo Tapia, María Cecilia; Lavandero González, Sergio (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2009-10-09)
      Myocyte enhancer factor 2C (MEF2C) plays an important role in cardiovascular development and is a key transcription factor for cardiac hypertrophy. Here, we describe MEF2C regulation by insulin-like growth factor-1 (IGF-1) ...